Browsing by Author "20ddfa59-0a4b-4f06-8f8a-4f7799401bb0"
Now showing items 1-3 of 3
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Lagos, Carlos F.; Araya Secchi, Raúl; Thomas, Pablo; Pérez-Acle, Tomás; Tapia, Ricardo A.; Salas, Cristian O. (2012)Trypanosoma cruzi glutamate cysteine ligase (TcGCL) is considered a potential drug target to develop novel antichagasic drugs. We have used a variety of computational methods to investigate the interactions between TcGCL ...
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Urzua, Julio I.; Contreras Ramos, Renato; Salas, Cristian O.; Tapia, Ricardo A. (2016)A new and efficient synthesis of 2-arylbenzoxazoles and benzothiazoles using a copper N-heterocyclic carbene complex is described. In a simple protocol a variety of 2-substituted benzoxazoles and benzothiazoles were obtained ...
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Salas, Cristian O.; Faúndez, Mario; Morello Casté, Antonio; Maya Arango, Juan; Tapia, Ricardo A. (2011)Chagas disease is one of the most important endemic diseases in Latin America, caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, nifurtimox and benznidazole, are toxic and present severe side ...