Browsing by Author "25c08691-f7b9-477a-921b-baf6ff6daeb4"

Now showing items 1-5 of 5

    • Autophagy protects against neural cell death induced by piperidine alkaloids present in Prosopis juliflora ... 
      Silva, Victor D.A.; Urriola Cuevas, Carlos; Muñoz, Patricia; Villa, Monica; Ahumada-Castro, Ulises; Huenchuguala, Sandro; Dos Santos, Cleonice C.; De Araujo, Fillipe M.; Ferreira, Rafael; Da Silva, Vanessa B.; Silva, Juliana H.C.; Soares, Érica N.; Velozo, Eudes S.; Segura Aguilar, Juan (Academia Brasileira de Ciencias, 2017)
      © 2017, Academia Brasileira de Ciencias. All rights reserved. Prosopis juliflora is a shrub that has been used to feed animals and humans. However, a synergistic action of piperidine alkaloids has been suggested to be ...
    • Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ ... 
      Cárdenas, César; Lovy, Alenka; Silva Pavéz, Eduardo; Urra Faúndez, Félix; Mizzoni, Craig; Ahumada Castro, Ulises; Bustos, Galdo; Jaña, Fabián; Cruz, Pablo; Farías, Paula; Mendoza, Elizabeth; Huerta, Hernán; Murgas, Paola; Hunter, Martín; Ríos, Melany; Cerda Arancibia, Oscar; Georgakoudi, Irene; Zakarian, Armen; Molgó, Jordi; Foskett, James Kevin (AAAS. American Association for the Advancement of Science, 2020)
      Spontaneous Ca2+ signaling from the InsP(3)R intracellular Ca2+ release channel to mitochondria is essential for optimal oxidative phosphorylation (OXPHOS) and ATP production. In cells with defective OXPHOS, reductive ...
    • FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via ... 
      Urra, Félix A.; Hernández Muñoz, Felipe Andrés; Córdova Delgado, Miguel; Ramírez, María Paz; Peña Ahumada, Bárbara; Rios, Melany; Cruz, Pablo; Ahumada-Castro, Ulises; Bustos, Galdo; Silva-Pavez, Eduardo; Pulgar Tejo, Rodrigo; Morales, Danna; Varela, Diego; Millas-Vargas, Juan Pablo; Retamal (Nature Publishing Group, 2018)
      © 2018, The Author(s).Highly malignant triple-negative breast cancer (TNBC) cells rely mostly on glycolysis to maintain cellular homeostasis; however, mitochondria are still required for migration and metastasis. Taking ...
    • Mitochondria and calcium regulation as basis of neurodegeneration associated with aging 
      Müller, Marioly; Ahumada-Castro, Ulises; Sanhueza, Mario; González Billault, Christian; Court, Felipe A.; Cárdenas, César (Frontiers Media S.A., 2018)
      © 2018 Müller, Ahumada-Castro, Sanhueza, Gonzalez-Billault, Court and Cárdenas.Age is the main risk factor for the onset of neurodegenerative diseases. A decline of mitochondrial function has been observed in several ...
    • MTOR-independent autophagy induced by interrupted endoplasmic reticulum-mitochondrial Ca2+ communication: ... 
      Ahumada-Castro, Ulises; Silva-Pavez, Eduardo; Lovy, Alenka; Pardo, Evelyn; Molgό, Jordi; Cárdenas, César (Taylor and Francis Inc., 2019)
      © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. The interruption of endoplasmic reticulum (ER)-mitochondrial Ca2+ communication induces a bioenergetic crisis characterized by an increase of MTOR-independent ...