Browsing by Author "2b19ec8a-4c31-4886-a30b-e74fbc4e1b94"

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    • Advances in Fetal and Neonatal Physiology 
      Giussani, Dino A.; Niu, Youguo; Herrera Videla, Emilio; Richter, Hans G.; Camm, Emily J.; Thakor, Avnesh S.; Kane, Andrew D.; Hansell, Jeremy A.; Brain, Kirsty L.; Skeffington, Katie L.; Itani, Nozomi; Wooding, F. B. Peter; Cross, Christine M.; Allison, Beth J. (Springer, 2014)
      The quality of the intrauterine environment interacts with our genetic makeup to shape the risk of developing disease in later life. Fetal chronic hypoxia is a common complication of pregnancy. This chapter reviews how ...
    • Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress 
      Giussani, Dino A.; Camm, Emily J.; Niu, Youguo; Richter, Hans G.; Blanco, Carlos E.; Gottschalk, Rachel; Blake, E. Zachary; Horder, Katy A.; Thakor, Avnesh S.; Hansell, Jeremy A.; Kane, Andrew D.; Wooding, F. B.Peter; Cross, Christine M.; Herrera, Emilio A. (2012)
      Fetal hypoxia is a common complication of pregnancy. It has been shown to programme cardiac and endothelial dysfunction in the offspring in adult life. However, the mechanisms via which this occurs remain elusive, precluding ...
    • Xanthine oxidase and the fetal cardiovascular defence to hypoxia in late gestation ovine pregnancy 
      Kane, Andrew D.; Hansell, Jeremy A.; Herrera, Emilio A.; Allison, Beth J.; Niu, Youguo; Brain, Kirsty L.; Kaandorp, Joepe J.; Derks, Jan B.; Giussani, Dino A. (2014)
      Hypoxia is a common challenge to the fetus, promoting a physiological defence to redistribute blood flow towards the brain and away from peripheral circulations. During acute hypoxia, reactive oxygen species (ROS) interact ...