Browsing by Author "3f9cb271-28c3-4b34-a0c3-4512fc4cde9f"
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D'Espessailles Tapia, Amanda; Santillana, Natalia; Sanhueza, Sofía; Fuentes, Cecilia; Cifuentes Koster, Mariana (Elsevier, 2020)Excess adipose tissue (AT) associates with inflammation and obesity-related diseases. We studied whether calcium-sensing receptor (CaSR)-mediated NLRP3 inflammasome activation in THP-1 macrophages elevates inflammation in ...
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Mattar, Pamela; Pino Sanhueza, Sofía Carolina; Yuri, Gabriela; Briones, Lautaro; Pérez Leighton, Claudio; Rudich, Assaf; Lavandero González, Sergio; Cifuentes Koster, Mariana (MDPI, 2020)Autophagy is upregulated in adipose tissue (AT) from people with obesity. We showed that activation of the calcium-sensing receptor (CaSR) elevates proinflammatory cytokines through autophagy in preadipocytes. Our aim is ...