Browsing by Author "43cc7a56-a9cb-4fae-ba2e-00cd36b3dbe6"

Now showing items 1-7 of 7

    • Central ceramide signaling mediates obesity-induced precocious puberty 
      Heras, Violeta; Castellano, Juan Manuel; Fernandois, Daniela; Velasco, Inmaculada; Rodríguez Vázquez, Elvira; Roa, Juan; Vázquez, María Jesús; Ruiz Pino, Francisco; Rubio, Matías; Pineda, Rafael; Torres, Encarnación; Avendaño, María Soledad; Paredes Vargas, Alfonso; Pinilla, Leonor; Belsham, Denise; Dieguez, Carlos; Gaytan, Francisco; Casals, Nuria; López, Miguel; Tena Sempere, Manuel (Cell, 2020)
      Childhood obesity, especially in girls, is frequently bound to earlier puberty, which is linked to higher disease burden later in life. The mechanisms underlying this association remain elusive. Here we show that brain ...
    • Effects of sympathectomy on ovarian follicular development and steroid secretion 
      Garrido Palma, Maritza; Fernandois, Daniela; Venegas Santos, Mauricio; Paredes Vargas, Alfonso (Bioscientifica Ltd., 2018)
      Recently, the influence of adrenergic activity over ovarian function, and thus fertility, has begun to gain importance. Previous studies have shown that adrenergic activity through norepinephrine (NE) participates in the ...
    • Increase in endogenous estradiol in the progeny of obese rats is associated with precocious puberty and ... 
      Ambrosetti, Valery; Guerra, Marcelo; Ramírez, Luisa A.; Reyes, Aldo; Álvarez, Daniela; OlguÍn, SofÍa; Gonzálz Mañan, Daniel; Fernandois, Daniela; Sotomayor Zárate, Ramón; Cruz, Gonzalo (Springer, 2016)
      Maternal obesity during pregnancy has been related with several pathological states in offspring. However, the impact of maternal obesity on reproductive system on the progeny is beginning to be elucidated. In this work, ...
    • Increases in norepinephrine release and ovarian cyst formation during ageing in the rat 
      Acuña, Eric; Fornes, Romina; Fernandois, Daniela; Garrido, Maritza P.; Greiner, Monika; Lara Peñaloza, Hernán; Paredes, Alfonso H. (2009)
      Background: Depletion of ovarian follicles is associated with the end of reproductive function in ageing females. Recently, it has been described that this process parallels increases in the concentration of norepinephrine ...
    • Kisspeptin level in the aging ovary is regulated by the sympathetic nervous system 
      Fernandois, Daniela; Cruz, Gonzalo; Na, Eun Kyung; Lara Peñaloza, Hernán; Paredes, Alfonso (BioScientifica Ltd., 2017)
      Previous work has demonstrated that the increase in the activity of sympathetic nerves, which occurs during the subfertility period in female rats, causes an increase in follicular cyst development and impairs follicular ...
    • Ovarian function and reproductive senescence in the rat: Role of ovarian sympathetic innervation 
      Cruz, Gonzalo; Fernandois, Daniela; Paredes, Alfonso H. (BioScientifica Ltd., 2017)
      © 2017 Society for Reproduction and Fertility. Successful reproduction is the result of a myriad interactions in which the ovary and the ovarian follicular reserve play a fundamental role. At present, women who delay ...
    • Prenatal metformin treatment improves ovarian function in offspring of obese rats 
      Álvarez, Daniela; Ceballo, Karina; Olguín, Sofía; Martínez Pinto, Jonathan Eloy; Maliqueo Yevilao, Manuel; Fernandois, Daniela; Sotomayor Zárate, Ramón; Cruz, Gonzalo (BioScientifica Ltd., 2018)
      Maternal obesity causes a wide range of impairment in offspring, such as metabolic and reproductive dysfunctions. We previously demonstrated that female offspring of obese rats have increased serum estradiol levels during ...