Now showing items 1-7 of 7

    • Michels, Karin B.; Keller, Kristen; Pereira, Ana; Kim, Claire E.; Santos, José L.; Shepherd, John A.; Corvalán, Camila; Binder, Alexandra M. (BMC, 2020)
      Background Systemic inflammation may play a role in shaping breast composition, one of the strongest risk factors for breast cancer. Pubertal development presents a critical window of breast tissue susceptibility to exogenous ...
    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Calafat, Antonia M.; Ye, Xiaoyun; Mericq, Verónica; Pereira Scalabrino, Ana; Michels, Karin B. (BIOMED Central Ltd., 2018)
      Background: The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposure ...
    • Gaskins, Audrey J.; Pereira Scalabrino, Ana; Quintiliano Scarpelli, Daiana; Shepherd, John A.; Uauy Dagach-Imbarack, Ricardo; Corvalán Aguilar, Camila; Michels, Karin B. (American Society for Nutrition, 2017-05-01)
      Background: Frequent dairy consumption in childhood has been related to higher growth-hormone concentrations that may affect mammary gland and pubertal development. Objective: We evaluated the relation of dairy intake ...
    • López, Ana; Garmendia Miguel, María Luisa; Shepherd, John; Michels, Karin; Corvalán Aguilar, Camila; Pereira Scalabrino, Ana (Nature, 2020)
      The effect of excessive gestational weight gain (EGWG) is related to adverse health outcomes in the offspring; however, its effect on the daughters' breast density is unclear. We aimed to assess the association between ...
    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Mericq, Verónica; Pereira Scalabrino, Ana; Santos, José Luis; Horvath, Steve; Shepherd, John; Michels, Karin B. (Taylor & Francis, 2018)
      Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a ...
    • Binder, Alexandra M.; Stiemsma, Leah T.; Keller, Kristen; Van Otterdijk, Sanne D.; Mericq, Verónica; Pereira, Ana; Santos, José Luis; Shepherd, John; Michels, Karin B. (BioMed Central Ltd., 2018)
      © 2018 The Author(s). Background: Estrogen receptor-α (ER-α) is a transcriptional regulator, which mediates estrogen-dependent breast development, as well as breast tumorigenesis. The influence of epigenetic regulation of ...
    • Gaskins, Audrey J.; Corvalán Aguilar, Camila; Michels, Karin B. (The American Society for Nutrition, 2017)