Now showing items 1-8 of 8

    • Advances in Fetal and Neonatal Physiology 

      Giussani, Dino A.; Niu, Youguo; Herrera Videla, Emilio; Richter, Hans G.; Camm, Emily J.; Thakor, Avnesh S.; Kane, Andrew D.; Hansell, Jeremy A.; Brain, Kirsty L.; Skeffington, Katie L.; Itani, Nozomi; Wooding, F. B. Peter; Cross, Christine M.; Allison, Beth J. (Springer, 2014)
      The quality of the intrauterine environment interacts with our genetic makeup to shape the risk of developing disease in later life. Fetal chronic hypoxia is a common complication of pregnancy. This chapter reviews how ...
    • Clock gene expression in adult primate suprachiasmatic nuclei and adrenal: Is the adrenal a peripheral clock responsive to melatonin? 

      Valenzuela, F. J.; Torres Farfán, Claudia; Richter, Hans G.; Méndez, N.; Campino, C.; Torrealba, F.; Valenzuela, G. J.; Serón Ferré, María (ENDOCRINE SOC, 2008-04)
      The circadian production of glucocorticoids involves the concerted action of several factors that eventually allow an adequate adaptation to the environment. Circadian rhythms are controlled by the circadian timing ...
    • Developmental Programming of Capuchin Monkey Adrenal Dysfunction by Gestational Chronodisruption 

      Richter, Hans G.; Mendez, Natalia; Abarzúa Catalán, Lorena; Valenzuela, Guillermo J.; Serón Ferré, María; Torres Farfán, Claudia (Hindawi Limited, 2018)
      © 2018 Hans G. Richter et al. In the capuchin monkey (Cebus apella), a new-world nonhuman primate, maternal exposure to constant light during last third of gestation induces precocious maturation of the fetal adrenal and ...
    • Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress 

      Giussani, Dino A.; Camm, Emily J.; Niu, Youguo; Richter, Hans G.; Blanco, Carlos E.; Gottschalk, Rachel; Blake, E. Zachary; Horder, Katy A.; Thakor, Avnesh S.; Hansell, Jeremy A.; Kane, Andrew D.; Wooding, F. B.Peter; Cross, Christine M.; Herrera, Emilio A. (2012)
      Fetal hypoxia is a common complication of pregnancy. It has been shown to programme cardiac and endothelial dysfunction in the offspring in adult life. However, the mechanisms via which this occurs remain elusive, precluding ...
    • Maternal-to-fetal allopurinol transfer and xanthine oxidase suppression in the late gestation pregnant rat 

      Kane, Andrew D.; Camm, Emily J.; Richter, Hans G.; Lusby, Ciara; Tijsseling, Deodata; Kaandorp, Joepe J.; Derks, Jan B.; Ozanne, Susan E.; Giussani, Dino A. (American Physiological Society, 2013)
      © 2013 The Authors. Fetal brain hypoxic injury remains a concern in high-risk delivery. There is significant clinical interest in agents that may diminish neuronal damage during birth asphyxia, such as in allopurinol, an ...
    • Mt1 melatonin receptor in the primate adrenal gland: Inhibition of adrenocorticotropin-stimulated cortisol production by melatonin 

      Torres Farfán, Claudia; Richter, Hans G.; Rojas García, Pedro; Vergara, Marcela; Forcelledo, María Luisa; Valladares Boasi, Luis; Torrealba, Fernando; Valenzuela, Guillermo J.; Serón Ferré, María (2003)
      The pineal hormone melatonin participates in circadian, seasonal, and reproductive physiology. The presence of melatonin binding sites in human brain and peripheral tissues is well documented. However, in the mammalian ...
    • Rhythmic expression of functional MT1 melatonin receptors in the rat adrenal gland 

      Richter, Hans G.; Torres Farfán, Claudia; García Sesnich, Jocelyn; Abarzúa Catalán, Lorena; Henríquez Luna, Mauricio; Alvarez Felmer, Mauro; Gaete, Fernando; Rehren, Germán E.; Serón Ferré, María (ENDOCRINE SOC, 2008-03)
      We previously demonstrated that melatonin is involved in the regulation of adrenal glucocorticoid production in diurnal primates through activation of MT1 membrane-bound melatonin receptors. However, whether melatonin ...
    • Timed maternal melatonin treatment reverses circadian disruption of the fetal adrenal clock imposed by exposure to constant light 

      Méndez, Natalia; Abarzúa Catalán, Lorena; Vilches, Nelson; Galdames, Hugo A.; Spichiger, Carlos; Richter, Hans G.; Valenzuela, Guillermo J.; Serón Ferré, María; Torres Farfán, Claudia (2012)
      Surprisingly, in our modern 24/7 society, there is scant information on the impact of developmental chronodisruption like the one experienced by shift worker pregnant women on fetal and postnatal physiology. There are ...