Browsing by Author "4565049a-a658-4567-bb90-d872cfc7ceb9"

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    • Aminochrome decreases NGF, GDNF and induces neuroinflammation in organotypic midbrain slice cultures 
      Araujo, Fillipe M. de; Ferreir, Rafael S.; Souza, Cleide S.; Santos, Cleonice Creusa dos; Rodrigues, Tácio L. R. S.; Silva, Juliana Helena C. E.; Gasparotto, Juciano; Gelain, Daniel Pens; El-Bachá, Ramón S.; Costa, María de Fátima D.; Fonseca, José Claudio M.; Segura Aguilar, Juan; Costa, Silvia L.; Silva, Víctor Diógenes A. (Elsevier, 2018-05)
      Recent evidence shows that aminochrome induces glial activation related to neuroinflammation. This dopamine derived molecule induces formation and stabilization of alpha-synuclein oligomers, mitochondria dysfunction, ...