Browsing by Author "4d5e8e21-4a98-4053-ae92-7275a0879665"

Now showing items 1-3 of 3

    • Fibroblast Primary Cilia Are Required for Cardiac Fibrosis 
      Villalobos, Elisa; Criollo Céspedes, Alfredo; Schiattarella, Gabriele G.; Altamirano, Francisco; French, Kristin M.; May, Herman I.; Jiang, Nan; Nguyen, Ngoc Uyen Nhi; Romero, Diego; Roa, Juan Carlos; García Nannig, Lorena; Díaz Araya, Guillermo; Morselli, Eugenia; Ferdous, Anwarul (NLM (Medline), 2019)
      BACKGROUND: The primary cilium is a singular cellular structure that extends from the surface of many cell types and plays crucial roles in vertebrate development, including that of the heart. Whereas ciliated cells have ...
    • Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation 
      Torrealba, Natalia; Navarro Márquez, Mario F.; Vega Garrido, Valeria; Pedrozo Cibils, Zully; Romero, Diego; Eura, Yuka; Villalobos, Elisa; Carlos Roa, Juan; Chiong Lay, Mario; Kokame, Koichi; Lavandero González, Sergio (Nature Publishing Group, 2017)
      Cardiac hypertrophy is an adaptive response triggered by pathological stimuli. Regulation of the synthesis and the degradation of the Ca2+ channel inositol 1,4,5-trisphosphate receptor (IP3R) affects progression to cardiac ...
    • Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma 
      Espinoza, Jaime A.; Riquelme, Ismael; Sagredo, Eduardo A.; Rosa, Lorena; García, Patricia; Bizama, Carolina; Apud-Bell, María; Leal, Pamela; Weber, Helga; Benavente, Felipe; Vargas, Sergio; Romero, Diego; Kalergis, Alexis M.; Roa, Juan Carlos (Blackwell Publishing Ltd, 2019)
      Aims: Gallbladder cancer (GBC) is an aggressive tumour that is usually diagnosed at advanced stages and is characterised by a poor prognosis. Using public data of normal human tissues, we found that mRNA and protein levels ...