Browsing by Author "5335dd08-0dfe-43b3-9042-34659d84b815"

Now showing items 1-6 of 6

    • Androgen-regulated cardiac metabolism in aging men 
      Barrientos Briones, Genaro; Llanos Vidal, Paola; Basualto-Alarcón, Carla; Estrada Hormazábal, Manuel (Frontiers Media, 2020)
      The prevalence of cardiovascular mortality is higher in men than in age-matched premenopausal women. Gender differences are linked to circulating sex-related steroid hormone levels and their cardio-specific actions, which ...
    • Ca2+/ Calmodulin dependent protein kinase II and androgen signaling pathways modulate MEF2 activity in ... 
      Durán, Javier; Lagos, Daniel; Pavez, Mario; Troncoso, Mayarling F.; Ramos, Sebastián; Barrientos Briones, Genaro; Ibarra, Cristián; Lavandero González, Sergio; Estrada Hormazábal, Manuel (Frontiers media SA, 2017)
      Testosterone is known to induce cardiac hypertrophy through androgen receptor (AR)-dependent and -independent pathways, but the molecular underpinnings of the androgen action remain poorly understood. Previous work has ...
    • Calcium release mediated by redox-sensitive RyR2 channels has a central role in hippocampal structural ... 
      More, Jamileth Y.; Bruna, Barbara A.; Lobos, Pedro; Galaz, Jose L.; Figueroa, Paula L.; Namias, Silvia; Sánchez, Gina; Barrientos Briones, Genaro; Valdes Guerrero, Jose; Paula Lima, Andrea; Hidalgo Tapia, María Cecilia; Adasme, Tatiana (Mary Ann Liebert Inc publishers, 2018)
      Aims: Previous studies indicate that hippocampal synaptic plasticity and spatial memory processes entail calcium release from intracellular stores mediated by ryanodine receptor (RyR) channels. In particular, RyR-mediated ...
    • GSK-3β/NFAT Signaling is involved in testosterone-induced cardiac myocyte hypertrophy 
      Durán, Javier; Oyarce Díaz, César; Pavez Giani, Mario; Valladares, Denisse; Basualto Alarcón, Carla; Lagos, Daniel; Barrientos Briones, Genaro; Troncoso Magñin, Mayarling; Ibarra, Cristián; Estrada Hormazábal, Manuel; Basualto Alarcón, Carla (Public Library Science, 2016-12-15)
      Testosterone induces cardiac hypertrophy through a mechanism that involves a concerted crosstalk between cytosolic and nuclear signaling pathways. Nuclear factor of activated Tcells (NFAT) is associated with the promotion ...
    • High fat diet induced obesity produces spontaneous ventricular arrhythmias and increases the activity of ... 
      Sánchez, Gina; Araneda, Felipe; Peña, Juan Pedro; Finkelstein, José Pablo; Riquelme, Jaime A.; Montecinos, Luis; Barrientos Briones, Genaro; Llanos Vidal, Paola; Pedrozo Cibils, Zully; Said, Matilde; Bull Simpfendorfer, Ricardo; Donoso Laurent, Paulina (MDPI, 2018)
      Ventricular arrhythmias are a common cause of sudden cardiac death, and their occurrence is higher in obese subjects. Abnormal gating of ryanodine receptors (RyR2), the calcium release channels of the sarcoplasmic reticulum, ...
    • Triclosan impairs hippocampal neuronal function 
      Hidalgo Tapia, María Cecilia; Barrientos Briones, Genaro; More, J.; Adasme, T.; Arias Cavieres, A.; Valdes, I.; Vicente, J. M.; Hidalgo Tapia, Jorge; Valdés, J. L. (Wiley, 2017)