Browsing by Author "56c327ee-0e7c-4902-8b62-4e854a05cb10"

Now showing items 1-14 of 14

    • A Prospective Cohort Study of the Prevalence of Growth, Facial, and Central Nervous System Abnormalities ... 
      Kuehn, Devon; Aros, Sofia; Cassorla Goluboff, Fernando; Avaria, Maria; Unanue, Nancy; Henriquez, Cecilia; Kleinsteuber, Karin; Conca Binfa, Bárbara; Avila, Alejandra; Carter, Tonia C.; Conley, Mary R.; Troendle, James; Mills, James L. (2012)
      Background:Most children who are exposed to large quantities of alcohol in utero do not developfetal alcohol syndrome (FAS). Population-based prospective data on the risk of developing componentsof fetal alcohol spectrum ...
    • Aldosterone, plasma renin activity, and aldosterone/renin ratio in a normotensive healthy pediatric population 
      Martínez Aguayo, Alejandro; Aglony, Marlene; Campino, Carmen; Garcia, Hernan; Bancalari, Rodrigo; Bolte, Lillian; Avalos, Carolina; Loureiro, Carolina; Carvajal, Cristian A.; Avila, Alejandra; Perez, Viviana; Inostroza, Andrea; Fardella, Carlos E. (2010)
      Primary aldosteronism is an important cause of secondary hypertension and is suspected in adults with an aldosterone/renin ratio ≥25. The normal aldosterone/renin ratio is unknown in children. The aim was to establish serum ...
    • Changes in Nocturnal Leptin and Insulin Concentrations in Prepubertal Low Birth Weight Children after ... 
      Iñíguez Vila, Germán; Román, Rossana; Avila, Alejandra; Gunn, Ronald D.; Cassorla Goluboff, Fernando (2009)
      Background: There is limited information regarding the effects of IGF-I and/or IGFBP-3 on circulating leptin concentrations. Aim: To determine the effects of IGF-I on leptin and insulin concentrations, we examined leptin ...
    • Differences in body composition and energy expenditure in prepubertal children born term or preterm appropriate ... 
      Mericq, Verónica; Iñíguez Vila, Germán; Bazaes, Rodrigo; Bouwman, Carolien; Avila, Alejandra; Salazar, Teresa; Carrasco, Fernando (Walter de Gruyter GmbH, 2009)
      Small size at birth may result from fetal undernutrition which may occur at different times during gestation. Early postnatal catch-up growth and excess childhood weight gain are associated with an increased risk of adult ...
    • Effects of luteinizing hormone-releasing hormone analog-induced pubertal delay in growth hormone (GH)-deficient ... 
      Cassorla Goluboff, Fernando; Mericq, Verónica; Eggers, Martha; Avila, Alejandra; García, Cristian; Fuentes, Ariel; Rose, Susan R.; Cutler, Gordon B. (Endocrine Society, 1997)
      To study the effect of delaying epiphyseal fusion on the growth of GH- deficient children, we studied 14 pubertal, treatment naive. GH-deficient patients (6 girls and 8 boys) in a prospective, randomized, placebo- controlled ...
    • Effects of treatment with GH alone or in combination with LHRH analog on bone mineral density in pubertal ... 
      Mericq, Verónica; Gajardo, Héctor; Eggers, Martha; Avila, Alejandra; Cassorla Goluboff, Fernando (Endocrine Society, 2002)
      The aim of the present study was to assess the impact of treatment with GH with or without LHRH analog (LHRH-A) on bone mineralization of GH-deficient adolescents. We studied 17 pubertal, treatment-naive, GH-deficient ...
    • Growth hormone (GH) responses to GH-releasing peptide and to GH-releasing hormone in GH-deficient children 
      Mericq, Verónica; Cassorla Goluboff, Fernando; Garcia, Hernan; Avila, Alejandra; Bowers, Cyril Y.; Merriam, George R. (1995)
      The GH-releasing peptides (GHRPs) are a family of hexa- and heptapeptides that specifically stimulate GH secretion in normal adults and children. They would be an attractive potential form of therapy for GH deficiency (GHD) ...
    • IGF-IR/ERK content and response to IGF-I and insulin in adipocytes from small for gestational age children 
      Iñíguez Vila, Germán; Ormazábal Leiva, Paulina Fernanda; López, Teresa; Maldonado, Diego; Avila, Alejandra; Román, Rossana; Cassorla Goluboff, Fernando (2009)
      Background/Aims: The GH-IGF-I axis plays an important role on pre/postnatal growth in humans, and IGF-I regulates cell proliferation, differentiation, and metabolic homeostasis. The adipose tissue has an important function ...
    • Leptin and IGF-I/II during the first weeks of life determine body composition at 2 years in infants born ... 
      Hernández, María Isabel; Rossel, Katherine; Peña, Verónica; Cavada Chacón, Gabriel; Avila, Alejandra; Iñíguez Vila, Germán; Mericq, Verónica (2012)
      Rapid early growth is associated with adverse metabolic outcome. The aim of this study was to determine whether there are differences in body composition (BC) between very-low-birth-weight preterm (VLBWPT) infants born ...
    • Microstructural brain and multivoxel spectroscopy in very low birth weight infants related to insulin-like ... 
      Okuma, Cecilia; Hernández, M. Isabel; Rodríguez, Pablo; Porras Flores, Rodrigo Antonio; Avila, Alejandra; Cavada Chacón, Gabriel; Kopplin, Erika; Rossel, Katherine; Iñíguez Vila, Germán; Mericq, Verónica (2013)
      Background: Very low birth weight (VLBW) children have higher risk of neurologic disabilities and growth factors are essential for brain maturation. Aim: To assess whether there are differences in neurologic findings, ...
    • Ovarian function in adolescents with McCune-Albright syndrome 
      Sotomayor, Karina; Iñíguez Vila, Germán; Ugarte, Francisca; Villarroel, Claudio; López, Patricia; Avila, Alejandra; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando (2011)
      Objective: To evaluate ovarian function, especially ovulation rate, in adolescents with McCune-Albright syndrome (MAS) and a history of peripheral precocious puberty. Design: Prospective cross-sectional study. Setting: ...
    • Patterns of infancy growth and metabolic hormonal profile are different in very-low-birth-weight preterm ... 
      Hernández, María Isabel; Rossel, Katherine; Peña, Veronica; García, Mirna; Cavada Chacón, Gabriel; Avila, Alejandra; Iñíguez Vila, Germán; Mericq, Verónica (Karger, 2018)
      Background/Aims: An increased preterm birth survival rate is associated with long-term neurological and metabolic risks; thus, our aim was to evaluate whether early patterns of infancy anthropometry and metabolic hormonal ...
    • Relationship between insulin sensitivity and IGF-I sensitivity in low birth weight prepubertal children 
      Román, Rossana; Iñíguez Vila, Germán; Salazar, Teresa; Avila, Alejandra; Barrera, Alvaro; Mericq, Verónica; Attie, Kenneth M.; Cassorla Goluboff, Fernando (2008)
      Background: Insulin-like growth factor-I (IGF-I) and insulin are structurally related proteins with similar receptors and signal transduction systems. Aim: We postulate that some low birth weight (LBW) children may have ...
    • Serum fibroblast growth factor 21 levels are inversely associated with growth rates in infancy 
      Mericq, Verónica; De Luca, Francesco; Hernández, María Isabel; Peña, Verónica; Rossel, Katherine; Garcia, Mirna; Avila, Alejandra; Cavada Chacón, Gabriel; Iñíguez Vila, Germán (S. Karger AG, 2014)
      Background: Fibroblast growth factor 21 (FGF21) is a metabolic and growth regulator.Aim: To investigate the role of FGF21 during growth in infancy.Methods: Blood samples for FGF21, leptin, insulin and glucose were collected ...