Now showing items 1-7 of 7

    • (2S,R-S)-6-Phenyl-1-(p-tolylsulfinyl)-hexa-3(E),5(E)-dien-2-ol 

      Donoso Tauda, Oscar; Escobar, Carlos A.; Araya Maturana, Ramiro; Vega, Andrés (BLACKWELL PUBLISHING, 2006-10)
      The molecule of the title compound, C19H20O2S, corresponds to a chiral sulfinyldienol with two stereogenic centres, viz. the C atom susbtituted by the hydroxy group and the sulfinyl S atom. The molecule displays a V-shape ...
    • 4-(2-Hydroxyphenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine and the 2-(2,3-dimethoxyphenyl)-, 2-(3,4-dimethoxyphenyl)- and 2-(2,5-dimethoxyphenyl)-substituted derivatives 

      Escobar, C. A.; Donoso Tauda, Oscar; Araya Maturana, Ramiro; Vega, Andrés (BLACKWELL PUBLISHING, 2007-07)
      The 1,5-benzodiazepine ring system exhibits a puckered boatlike conformation for all four title compounds [4-(2-hydroxyphenyl)2- phenyl-2,3-dihydro-1H-1,5-benzodiazepine, C21H18N2O, (I), 2-(2,3-dimethoxyphenyl)-4-(2-hydr ...
    • Effects of simple and angular chromones on tumor cell respiration 

      Araya Maturana, Ramiro; Heredia Moya, Jorge; Donoso Tauda, Oscar; Vera Castillo, Mario Francisco; Toledo Hernández, Jorge; Pavani, Mario; Pessoa Mahana, Hernán; Weiss López, Boris; Ferreira Parker, Jorge (NATURAL PRODUCTS INC, 2008)
      A set of structurally related compounds incorporating a chromone moiety as an essential component of their structures were tested against the TA3 mouse carcinoma cell line and its multidrug-resistant variant TA3-MTX-R. A ...
    • Five bicyclo-[3.3.0]octa-2,6-dienes 

      Vega, Andrés; Donoso-Tauda, Oscar; Ibãez, Andres; Escobar, Carlos A. (2008)
      A series of five compounds containing the bicyclo-[3.3.0]octa-2,6-diene skeleton are described, namely tetra-methyl cis,cis-3,7-dihydroxy-bicyclo-[3.3. 0]octa-2,6-diene-2,4-exo,6,8-exo-tetracarboxyl-ate, C16H18O10, (I), ...
    • Five bicyclo[3.3.0]octa-2,6-dienes 

      Vega, Andrés; Donoso Tauda, Oscar; Ibáñez, Andrés; Escobar, Carlos (BLACKWELL PUBLISHING, 2008-04)
      A series of five compounds containing the bicyclo[3.3.0]octa-2,6-diene skeleton are described, namely tetramethyl cis,cis-3,7-dihydroxybicyclo[3.3.0]octa-2,6-diene-2,4-exo,6,8-exo-tetracarboxylate, C(16)H(18)O(10), (I), ...
    • Structural antitumoral activity relationships of synthetic chalcones 

      Echeverría, César; Santibáñez, Juan Francisco; Donoso Tauda, Óscar; Escobar, Carlos A.; Ramírez Tagle, Rodrigo (2009)
      Relationships between the structural characteristic of synthetic chalcones and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with synthetic 2'-hydroxychalcones resulted in apoptosis induction ...
    • Synthesis of 1,5-benzodiazepines with unusual substitution pattern from chalcones under solvent-free microwave irradiation conditions 

      Escobar, Carlos A.; Donoso Tauda, Oscar; Araya Maturana, Ramiro; Sicker, Dieter (2009)
      1,5-Benzodiazepines have been synthesized from the corresponding 2'-hydroxychalcones [1-(2-hydroxyphenyl)-3-aryl-2-propen-1-ones] and o-phenylenediamine, both in methanol, under reflux and under solvent-free microwave ...