Browsing by Author "5c7d57c9-7257-41f1-af40-d715e0254720"

Now showing items 1-6 of 6

    • Dead tumor cells expressing infectious salmon anemia virus fusogenic protein favor antigen cross-priming in vitro 
      Morales, Jonathan; Barrera Avalos, Carlos; Castro, Carlos; Castillo, Stephanie; Barrientos, Claudio; Robles Planells, Claudia; López, Ximena; Torres, Ernesto; Montoya, Margarita; Cortez San Martin, Marcelo; Riquelme, Denise; Escobar Álvarez, Alejandro; Fernández, Ricardo; Imarai, Mónica; Sauma Mahaluf, Daniela; Rojo, Leonel E.; Leiva Salcedo, Elias; Acuña Castillo, Claudio (Frontiers media SA, 2017)
      Antigen cross-presentation is a crucial step in the assembly of an antitumor immune response leading to activation of naive CD8 T cells. This process has been extensively used in clinical trials, in which dendritic cells ...
    • High-frequency field stimulation of primary neurons enhances ryanodine receptor-mediated Ca2+ release and ... 
      Riquelme, Denise; Alvarez, Alvaro; Leal, Nancy; Adasme, Tatiana; Espinoza, Italo; Valdés, Juan Antonio; Troncoso, Natalia; Hartel, Steffen; Segura Hidalgo, Jorge Antonio; Hidalgo Tapia, María Cecilia; Carrasco, M. Angélica (2011)
      Neuronal electrical activity increases intracellular Ca2+ concentration and generates reactive oxygen species. Here, we show that high frequency field stimulation of primary hippocampal neurons generated Ca 2+ signals with ...
    • Hypoxia stimulates via separate pathways ERK phosphorylation and NF-κB activation in skeletal muscle cells ... 
      Osorio Fuentealba, César; Valdés, Juan Antonio; Riquelme, Denise; Segura Hidalgo, Jorge Antonio; Hidalgo Tapia, María Cecilia; Carrasco, María Angélica (2009)
      Mammalian cells sense oxygen levels and respond to hypoxic conditions through the regulation of multiple signaling pathways and transcription factors. Here, we investigated the effects of hypoxia on the activity of two ...
    • K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and ... 
      Canales, Jimena; Cruz, Pablo; Villacura Díaz, Nicolás Esteban; Riquelme, Denise; Leiva Salcedo, Elias; Cerda Arancibia, Óscar (MDPI, 2020)
      Cell migration is critical for several physiological and pathophysiological processes. It depends on the coordinated action of kinases, phosphatases, Rho-GTPases proteins, and Ca2+ signaling. Interestingly, ubiquitination ...
    • Subcellular Localization and Activity of TRPM4 in Medial Prefrontal Cortex Layer 2/3 
      Riquelme, Denise; Silva, Ian; Philp, Ashleigh M.; Huidobro Toro, Juan Pablo; Cerda, Oscar; Trimmer, James; Leiva Salcedo, Elías (Frontiers Media SA, 2018)
      TRPM4 is a Ca2+-activated non-selective cationic channel that conducts monovalent cations. TRPM4 has been proposed to contribute to burst firing and sustained activity in several brain regions, however, the cellular and ...
    • TRPM4 activation by chemically- and oxygen deprivation-induced ischemia and reperfusion triggers neuronal death 
      Leiva Salcedo, Elias; Riquelme, Denise; Cerda Arancibia, Óscar; Stutzin Schottlander, Andrés (Taylor & Francis, 2017)
      Cerebral ischemia-reperfusion injury triggers a deleterious process ending in neuronal death. This process has two components, a glutamate-dependent and a glutamate-independent mechanism. In the glutamate-independent ...