Now showing items 1-2 of 2

    • Effects of antihypertensive treatment on cardiac IGF-1 during prevention of ventricular hypertrophy in the rat 

      Jalil Milad, Jorge; Ebensperger González, Roberto; Meléndez Vergara, Jaime; Acevedo, E.; Sapag Hagar, Mario; González Jara, Fabián Rodrigo; Gálvez, Anita; Pérez Montes, Viviana; Lavandero González, Sergio (PERGAMON-ELSEVIER SCIENCE LTD, 1999-03-26)
      There is some evidence that cardiac rather than circulating insulin-like growth factor-1 (IGF-1) levels contribute to the development of renovascular hypertensive left ventricular hypertrophy (LVH), remaining unknown the ...
    • Extracellular regulated kinase, but not protein kinase C, is an antiapoptotic signal of insulin-like growth factor-1 on cultured cardiac myocytes 

      Foncea Avila, Rocío; Gálvez, Anita; Pérez Montes, Viviana; Morales, María Paz; Calixto, Andrea; Meléndez Vergara, Jaime; González Jara, Fabián Rodrigo; Díaz Araya, Guillermo; Sapag Hagar, Mario; Sugden, Peter H.; LeRoith, Derek; Lavandero González, Sergio (ACADEMIC PRESS INC, 2000-07-05)
      This study aims to elucidate the signaling pathway for insulin-like growth factor-1 (IGF-1) in cultured neonatal rat cardiomyocytes and particularly the role of IGF-1 in cardiac apoptosis, IGF-1 stimulated polyphosphoinositide ...