Now showing items 1-7 of 7

    • Collagenase-like activity associated to the leukemic WEHI-3B cell line 

      Fernández Gálvez, Mireya; Martínez Winkler, Jorge; Minguell Uribe, José (1990)
      The leukemic cell line, WEHI-3B presents a latent collagenase-like activity which is activated after trypsin treatment. The enzymatic activity is not released from cells and is specific for the degradation of interstitial ...
    • Cryopreservation of rainbow trout (Oncorhynchus mykiss) spermatozoa using programmable freezing 

      Conget Molina, Paulette; Fernández Gálvez, Mireya; Herrera, Guillermo; Minguell Uribe, José (Elsevier B.V., 1996)
      In an attempt to establish a protocol for the cryopreservation of the spermatozoa of the rainbow trout (Oncorhynchus mykiss), we studied the effect of various cryoprotective agents (CA) in spermatozoa motility and viability, ...
    • Evidence for cooperative effects in human liver arginase 

      Carvajal Baeza, Nelson; Acoria García, Marina; Rodríguez Vives, Juan Pablo; Fernández Gálvez, Mireya; Martínez Winkler, Jorge (1982)
      The reaction kinetics of human liver arginase (l-arginine amidinohydrolase, EC 3.5.3.1) in terms of arginine concentration is strikingly altered by varying the pH. Lowering the pH from the optimum (9.5) toward a more ...
    • Interstitial collagen synthesis by somatic testicular cells in culture 

      Rodriguez, J. Pablo; Fernández, Mireya; Minguell, Jośe J. (1991)
      The synthesis, distribution and types of collagen produced by somatic testicular cells in culture was studied. To investigate whether changes in collagen synthesis correlate with the age of the animal, cultures derived ...
    • The increased expression of receptor activator of nuclear-κB ligand (RANKL) of multiple myeloma bone marrow stromal cells is inhibited by the bisphosphonate ibandronate 

      Fernández, Mireya; Pino, Ana M.; Figueroa, Paula; Rodríguez, Juan P. (2010)
      The receptor activator of nuclear factor-kappaB ligand (RANKL) and interleukin-1beta are osteoclast activating factors which are abnormally expressed in bone marrow stromal cells and plasma cells of multiple myeloma patients. ...
    • Urease of Spirulina maxima 

      Carvajal, Nelson; Fernández, Mireya; Pablo Rodríguez, Juan; Donoso, Margarita (1980)
      Urease (EC 3.5.1.5) was purified from Spirulina maxima by ammonium sulfate precipitation, DEAE-cellulose chromatography and gel filtration on Sephadex G-200. The enzyme had maximum activity at pH 8.7, a Km for urea of 0.12 ...
    • Weight increase and overweight are associated with DNA oxidative damage in skeletal muscle 

      Maza Cave, María Pía de la; Olivares, Daniela; Hirsch Birn, Sandra; Sierralta, Walter; Gattas, Vivien; Barrera Acevedo, María; Bunout Barnett, Daniel; Leiva Balich, Laura; Fernández, Mireya (CHURCHILL LIVINGSTONE, 2006-12)
      Background and aims: Weight maintenance within normal standards is recommended for prevention of conditions associated with oxidative injury. To compare oxidative damage in a post mitotic tissue, between adults differing ...