Browsing by Author "65d2f64f-6981-438c-a925-b98f6838ed6f"

Now showing items 1-3 of 3

    • ADP-dependent kinases from the archaeal order methanosarcinales adapt to salt by a non-canonical evolutionarily ... 
      González Órdenes, Felipe; Cea, Pablo A.; Fuentes, Nicolás; Muñoz, Sebastián M.; Zamora, Ricardo A.; Leonardo, Diego; Garratt, Richard C.; Castro Fernández, Víctor; Guixé Leguía, Victoria Cristina (Frontiers Media SA., 2018-06-26)
      Halophilic organisms inhabit hypersaline environments where the extreme ionic conditions and osmotic pressure have driven the evolution of molecular adaptation mechanisms. Understanding such mechanisms is limited by the ...
    • Evolution, metabolism and molecular mechanisms underlying extreme adaptation of euryarchaeota and its ... 
      Castro Fernández, Víctor; Zamora, Ricardo; Herrera Morandé, Alejandra; Vallejos, Gabriel; González Órdenes, Felipe; Guixé Leguía, Victoria Cristina (IntechOpen, 2017)
      Archaeal organisms harbor many unique genotypic and phenotypic properties, testifying their peculiar evolutionary status. Thus, the so‐called extremophiles must be adequately adapted to cope with many extreme environments ...
    • Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity ... 
      Castro Fernández, Víctor; Herrera Morande, Alejandra; Zamorano Sarria, Ricardo; Merino, Felipe; González Órdenes, Felipe; Padilla Salinas, Felipe; Pereira, Humberto M.; Brandao Neto, José; Garratt, Richard C.; Guixé Leguía, Victoria Cristina (American Society for Biochemistry and Molecular Biology, 2017)
      One central goal in molecular evolution is to pinpoint the mechanisms and evolutionary forces that cause an enzyme to change its substrate specificity; however, these processes remain largely unexplored. Using the glycolytic ...