Browsing by Author "7119d4b1-67d8-40d8-b112-914fa2e57d42"

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    • Evaluación del consumo de antimicrobianos en una Unidad de Neonatología: un trabajo en equipo para promover ... 
      Jiménez, Elisa; Valls Jiménez, Nicolás; Astudillo, Patricio; Valls, Cristian; Cavada Chacón, Gabriel; Sandoval, Alejandra; Alegría, Angélica; Ortega, Gabriela; Núñez, Daniela; Mena, Patricia (Sociedad Chilena de Infectología, 2017)
      Background: Antibiotics (ATB) are drugs widely used in hospitalized newborns. The indiscriminate use of ATBs promote the rise of resistant bacteria to the most commonly indicated antimicrobials. In addition, ATB prescription ...
    • Genotoxic stress triggers the activation of IRE1 alpha-dependent RNA decay to modulate the DNA damage response 
      Dufey, Estefanie; Bravo San Pedro, José; Eggers Aracena, Cristián; González Quiroz, Matías; Urra Zúñiga, Hery; Sagredo Campos, Alfredo; Sepúlveda Alvarado, Denisse; Pihán Najle, Philippe; Carreras Sureda, Armando; Hazari, Younis; Sagredo, Eduardo A.; Gutiérrez, Daniela; Valls, Cristian; Papaioannou, Alexandra; Acosta Alvear, Diego; Campos, Gisela; Domingos, Pedro M.; Pedeux, Rémy; Chevet, Eric; Álvarez, Alejandra R.; Godoy, Patricio; Walter, Peter; Glavic Maurer, Álvaro; Kroemer, Guido; Hetz Flores, Claudio (Nature, 2020)
      The molecular connections between homeostatic systems that maintain both genome integrity and proteostasis are poorly understood. Here we identify the selective activation of the unfolded protein response transducer IRE1 ...