Browsing by Author "73c6b018-4d7e-43ef-bb22-dd8263f678a2"
Now showing items 1-8 of 8
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Estrogen metabolites in human corpus luteum physiology: differential effects on angiogenic activity Henríquez, Soledad; Kohen Skop, Paulina; Xu, Xia; Veenstra, Timothy D.; Muñoz, Alex; Palomino Avilés, Wilder; Strauss, Jerome F.; Devoto, Luigi (Elsevier, 2016)Objective: To determine tissue concentrations of E2, estrone, P, and estrogensmetabolites (EMs) 2-methoxyestradiol, 2-methoxyestrone, 4-hydroxyestrone, and 16-ketoestradiol in corpus luteum(CL) of different ages, and after ...
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Del Canto, Felipe; Sierralta, Walter; Kohen Skop, Paulina; Ferrada Muñoz, Alex Eduardo; Strauss, Jerome F.; Devoto, Luigi (Endocrine Society, 2007)Context: The natural process of luteolysis and luteal regression is induced by withdrawal of gonadotropin support. Objective: The objectives of this study were: 1) to compare the functional changes and apoptotic features ...
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Human corpus luteum physiology and the luteal-phase dysfunction associated with ovarian stimulation Devoto, Luigi; Kohen Skop, Paulina; Ferrada Muñoz, Alex Eduardo; Strauss, Jerome F. (Reproductive Healthcare Ltd, 2009)The human corpus luteum is a temporary endocrine gland that develops after ovulation from the ruptured follicle during the luteal phase. It is an important contributor of steroid hormones, particularly progesterone, and ...
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Henríquez Barrera, Soledad; Kohen Skop, Paulina; Muñoz Gallardo, Alex; Godoy, Ana; Orge, Felipe; Strauss, Jerome F.; Devoto, Luigi (Elsevier, 2017)In humans, data on gonadotrophin-activated (LH, HCG and FSH) progesterone receptor expression and signalling pathways involved in matrix metalloproteinases (MMPs) expression presumably linked to the follicle rupture, are ...
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Poch, Andrea; Villanelo, Felipe; Henriquez, Soledad; Kohen Skop, Paulina; Ferrada Muñoz, Alex Eduardo; Strauss, Jerome F.; Devoto, Luigi (Elsevier Inc., 2019)An estradiol metabolite, 2-methoxyestradiol (2ME), has emerged as an important regulator of ovarian physiology. 2ME is recognized as a potent anti-angiogenic agent in clinical trials and laboratory studies. However, little ...
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Henríquez Barrera, Soledad; Kohen, Paulina; Xu, Xia; Villarroel Quintana, Claudio; Muñoz Gallardo, Alex; Godoy, Ana; Strauss, Jerome F; Devoto, Luigi (Oxford, 2020)STUDY QUESTION: Do alterations in pro- and anti-angiogenic estrogen metabolites in follicular fluid (FF) contribute to the follicular growth arrest and anovulation associated with polycystic ovary syndrome (PCOS)? SUMMARY ...
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Devoto, Luigi; Henríquez, Soledad; Kohen Skop, Paulina; Strauss, Jerome F. (Elsevier, 2017)The human corpus luteum (CL) is a temporary endocrine gland derived from the ovulated follicle. Its formation and limited lifespan is critical for steroid hormone production required to support menstrual cyclicity, endometrial ...
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Kohen Skop, Paulina; Castro, Olga; Palomino, Alberto; Muñoz, Alex; Christenson, Lane K.; Sierralta, Walter; Carvallo, Pilar; Strauss, Jerome F.; Devoto, Luigi (2003)This study was designed 1) to assess corpus luteum (CL) steroidogenesis in response to exogenous human chorionic gonadotropin (hCG) at different times during the luteal phase, 2) to examine the effect of hCG on steroidogenic ...