Browsing by Author "73c77dc8-03e1-4bb4-8821-4c95cbd2ee2e"

Now showing items 1-8 of 8

    • A novel immunomodulatory hemocyanin from the limpet Fissurella latimarginata promotes potent anti-tumor ... 
      Arancibia, Sergio; Espinoza, Cecilia; Salazar, Fabián; Del Campo, Miguel; Tampe, Ricardo; Zhong, Ta Ying; Ioannes, Pablo de; Moltedo, Bruno; Ferreira, Jorge; Lavelle, Ed C.; Manubens, Augusto; Ioannes, Alfredo de; Becker, María Inés (Public Library of Science, 2014)
      Hemocyanins, the huge oxygen-transporting glycoproteins of some mollusks, are used as immunomodulatory proteins with proven anti-cancer properties. The biodiversity of hemocyanins has promoted interest in identifying new ...
    • Concholepas hemocyanin biosynthesis takes place in the hepatopancreas, with hemocytes being involved in its ... 
      Manubens, Augusto; Salazar, Fabián; Haussmann, Denise; Figueroa, Jaime; Del Campo, Miguel; Pinto, Jonathan Martínez; Huaquín, Laura; Venegas, Alejandro; Becker, María Inés (2010)
      Hemocyanins are copper-containing glycoproteins in some molluscs and arthropods, and their bestknown function is O2 transport. We studied the site of their biosynthesis in the gastropod Concholepas concholepas by using ...
    • Hemocianinas, una herramienta inmunológica de la biomedicina actual 
      Campo, Miguel del; Arancibia, Sergio; Nova, Esteban; Salazar, Fabián; González, Andrea; Moltedo, Bruno; Ioannes, Pablo de; Ferreira, Jorge; Manubens, Augusto; Becker, María Inés (Sociedad Médica de Santiago, 2011-02)
    • Hemocyanins as immunostimulants Hemocianinas, una herramienta inmunológica de la biomedicina actual 
      del Campo, Miguel; Arancibia, Sergio; Nova, Esteban; Salazar, Fabián; González, Andrea; Moltedo, Bruno; Ioannes, Pablo de; Ferreira, Jorge; Manubens, Augusto; Becker, María Inés (2011)
      Hemocyanins, the giant oxygen transporter glycoproteins of diverse mollusks, are xenogenic to the mammalian immune system and they display a remarkable immunogenicity. Therefore they are ideal non-specific immunostimulants ...
    • Immunodominant role of CCHA subunit of Concholepas hemocyanin is associated with unique biochemical properties 
      Becker, María Inés; Fuentes, Alejandra; Del Campo, Miguel; Manubens, Augusto; Nova, Esteban; Oliva, Harold; Faunes, Fernando; Valenzuela, María Antonieta; Campos Vallette, Marcelo; Aliaga, Alvaro E.; Ferreira, Jorge; Ioannes, Alfredo de; Ioannes, Pablo de; Moltedo, Br (2009)
      Hemocyanin, the oxygen transporter metallo-glycoprotein from mollusks, shows strong relationship between its notable structural features and intrinsic immunomodulatory effects. Here we investigated the individual contribution ...
    • Immunotherapeutic potential of mollusk hemocyanins in combination with human vaccine adjuvants in murine ... 
      Román, Juan José Mora; Del Campo, Miguel; Villar, Javiera; Paolini, Francesca; Curzio, Gianfranca; Venuti, Aldo; Jara, Lilian; Ferreira, Jorge; Murgas, Paola; Lladser, Alvaro; Manubens, Augusto; Becker, María Inés (Hindawi Limited, 2019)
      Mollusk hemocyanins have been used for decades in immunological and clinical applications as natural, nontoxic, nonpathogenic, and nonspecific immunostimulants for the treatment of superficial bladder cancer, as ...
    • The oxygen binding properties of hemocyanin from the mollusk Concholepas concholepas 
      González, Andrea; Nova, Esteban; Campo, Miguel del; Manubens, Augusto; Ioannes, Alfredo de; Ferreira Parker, Jorge; Becker, María Inés (Elsevier, 2017)
      Hemocyanins have highly conserved copper-containing active sites that bind oxygen. However, structural differences among the hemocyanins of various mollusks may affect their physicochemical properties. Here, we studied ...
    • The oxygen-binding properties of hemocyanin from the mollusk Concholepas concholepas 
      González, Andrea; Nova, Esteban; Del Campo, Miguel; Manubens, Augusto; Ioannes, Alfredo de; Ferreira, Jorge; Becker, María Inés (Elsevier B.V., 2017)
      © 2017 Elsevier B.V. Hemocyanins have highly conserved copper-containing active sites that bind oxygen. However, structural differences among the hemocyanins of various mollusks may affect their physicochemical properties. ...