Now showing items 1-20 of 39

    • San Martín Barrientos, Aurelio; Bacho, M.; Núñez, S.; Rovirosa, Juana; Soler, A.; Blanc, V.; León, R.; Olea, Andrés F. (Sociedad Chilena de Quimica, 2018)
      © 2018 Sociedad Chilena de Quimica.all rights reserved. Phytochemical analysis of Azorella compacta resulted in the isolation of six known diterpenes and one unknown norditerpene using chromatographic methods. The structure ...
    • Muñoz, Marcelo A.; Areche, Carlos; Rovirosa, Juana; San Martín Barrientos, Aurelio; Joseph-Nathan, Pedro (2010)
      The absolute configuration (AC) of sargaol acetate (2), isolated from the brown alga Stypopodium flabelliforme, was determined using vibrational circular dichroism (VCD) measurements and density functional theory (DFT) ...
    • Muñoz, Marcelo A.; Areche, Carlos; Rovirosa, Juana; San Martín Barrientos, Aurelio; Gordillo Román, Bárbara; Joseph Nathan, Pedro (2012)
      The absolute configuration of alga meroditerpenoids (-)-taondiol diacetate (1b) and (+)-epitaondiol diacetate (2c) are assigned by vibrational circular dichroism (VCD). The spectra of (2S,3S,6R,7R,10R,11R,14S)-1b and ...
    • Areche Medina, Carlos; San Martín Barrientos, Aurelio; Rovirosa, Juana; Soto Delgado, Jorge; Contreras Ramos, Renato (Elsevier, 2009-08-19)
      Meroditerpenoids, 2-[20(E)-30,70,110,150-tetramethylhexadec-2-en-10-yl]-6-methyl-1,4-benzohydroquinone diacetate and 40-chlorostypotriol triacetate, along with eight known compounds isolated from the dichloromethane ...
    • Pereira, David M.; Cheel, Jose; Areche, Carlos; San Martín Barrientos, Aurelio; Rovirosa, Juana; Silva, Luis R.; Valentao, Patricia; Andrade, Paula B. (2011)
      The sea constitutes one of the most promising sources of novel compounds with potential application in human therapeutics. In particular, algae have proved to be an interesting source of new bioactive compounds. In this ...
    • Argandoña, Victor H.; Rovirosa, Juana; San Martín Barrientos, Aurelio; Torres Riquelme, Alejandro; Díaz Marrero, Ana; Cueto, Mercedes; Darias, José; Santana, Omar; Guadaño, Ana; González-Coloma, Azucena (2002)
      In this work the antifeedant effects of the halogenated monoterpenes 1-13 were tested against several divergent insect species. These compounds have been isolated from Plocamium cartilagineum (6 was isolated as an acetyl ...
    • Donoso, Viviana; Bacho, Mitchell; Núñez, Solange; Rovirosa, Juana; San Martín Barrientos, Aurelio; Leiva, Sergio (Natural Products, 2015)
      The present study was aimed at evaluating the antibacterial activity of mulinane and azorellane diterpenes isolated from the Andean plants Azorella compacta and A. trifoliolata and semisynthetic derivatives against ...
    • Chamy, Maria Cristina; Orejarena, Silvia; Rovirosa, Juana; San Martín Barrientos, Aurelio (Sociedad Chilena de Quimica, 2013)
      ABSTRACT The microbiological transformation of ent-beyer-15-en-18-ol 1 and ent-beyer-15-en-19-ol 2, using Mucor plumbeus, resulted in hydroxylated products. After nine days of incubation, 15?,16?-epoxide-ent-beyeran-7b,18-diol ...
    • Areche, Carlos; Vaca Cerezo, Inmaculada; Labbe, Pamela; Soto Delgado, Jorge; Astudillo, Luis; Silva, Mario; Rovirosa, Juana; San Martín Barrientos, Aurelio (2011)
      Biological transformation of the meroditerpenoid, stypotriol triacetate (1) by the fungi Aspergillus niger, Cunninghamella elegans, Gibberella fujikuroi and Mucor plumbeus was studied. The incubation of 1 with A. niger ...
    • San Martín Barrientos, Aurelio; Rovirosa, Juana; Astudillo, Luis; Sepúlveda, Beatriz; Ruiz, Daniela; San Martín Rovirosa, Carol (TAYLOR & FRANCIS LTD, 2008-01-09)
      Continued investigation of the marine alga Laurencia claviformis has led to the isolation of pacifenol, a halogenated sesquiterpene as the major metabolite. The microbial transformation of pacifenol is reported. It was ...
    • Depix, María S.; Martínez, Jorge; Santibañez, Francisco; Rovirosa, Juana; San Martín Barrientos, Aurelio; Maccioni Baraona, Ricardo (1998)
      We investigated the effects of the drug 14-keto-stypodiol diacetate (SDA) extracted from the seaweed product Stypopodium flabelliforme, in inhibiting the cell growth and tumor invasive behavior of DU-145 human prostate ...
    • Peters, K.; Peters, E. M.; von Schnering, H. G.; Manríquez Castro, Víctor; Rovirosa, Juana (1996)
    • Muñoz, Marcelo A.; Chamy, Cristina; Carrasco, Alvaro; Rovirosa, Juana; San Martín Barrientos, Aurelio; Joseph Nathan, Pedro (WILEY-BLACKWELL, 2009-11-06)
      The configuration of a chiral center in semisynthetic (2)-(2R,5R,5aR,8f,9aS)- 2,8-dibromo-2,5,9,9a-tetrahydro-5-hydroxy-5,8,10,10-tetramethyl-6H-2,5a-methano-1-benzoxepin- 7(8H)-one (3 or 4), prepared in two steps from ...
    • Areche Medina, Carlos; Vaca Cerezo, Inmaculada; Loyola, Luis Alberto; Bórquez, Jorge; Rovirosa, Juana; San Martín Barrientos, Aurelio (GEORG THIEME VERLAG KG, 2010-10)
      Two new diterpenoids, mulin-12-en-16-al-20-oic acid and 13-alpha-hydroxy-mulin-11-en-14-one-20-oic acid, were isolated from Azorella madreporica. Their structures were identified on the basis of one-dimensional and ...
    • Palma, Rodrigo; Edding, Mario; Rovirosa, Juana; San Martín Barrientos, Aurelio; Argandoña, Victor (Verlag der Zeitschrift fur Naturforschung, 2004)
      The effect of different photon flux densities (PFD) and temperatures on the relative growth rate (RGR) and the concentration of three halogenated monoterpenes in samples of Plocamium cartilagineum L.( Dixon), a marine alga ...
    • Areche, Carlos; San Martín Barrientos, Aurelio; Rovirosa, Juana; Sepúlveda, Beatriz (2011)
      The effects of epitaondiol (1) and sargaol (2), isolated from the brown alga Stypopodium flabelliforme on HCl/ethanol-induced gastric lesions in mice were evaluated and compared with that of lansoprazole. Epitaondiol and ...
    • Cancino Rivera, Patricio Antonio; Astudillo, Luis; Rovirosa, Juana; San Martín Barrientos, Aurelio (1987)
    • San Martín Barrientos, Aurelio; Negrete, Rosa; Rovirosa, Juana (1991)
      Four new alicyclic monoterpenes based on the 1-(2-chlorovinyl)-2,4,5-trichloro-1,5-dimethylcyclohexane skeleton were isolated from Plocamium cartilagineum from the Chilean coast, together with four known cyclic monoterpenes. ...
    • San Martín Barrientos, Aurelio; Quezada, Elías; Soto, Pilar; Palacios, Yolanda; Rovirosa, Juana (Natl Research Council of Canada, 1996)
      The marine gastropod mollusk *Trimusculus peruvianus collected on the coast of Central Chile yielded four new labdane metabolites. The structural elucidation of all compounds was accomplished by spectral analysis. One ...
    • San Martín Barrientos, Aurelio; Rovirosa, Juana; Carrasco, Alvaro; Orejarena, Silvia; Soto Delgado, Jorge; Contreras Ramos, Renato; Chamy, M. Cristina (Editorial Board, 2010-11-12)
      The sesquiterpene pacifenol is one of the main constituents of the red alga Laurencia claviformis. Earlier work on the semisynthetic derivatives of pacifenol afforded a series of halogenated sesquiterpenes. The aim of the ...