Now showing items 1-5 of 5

    • A novel in vivo model to study impaired tissue regeneration mediated by cigarette smoke 

      Alvarez, Marjorie; Chavez, Myra; Calorio Miranda, Miguel; Aedo, Geraldine; Allende Connelly, Miguel; Egaña, José (Nature Publishing Group, 2018-07-19)
      Cigarette smoke is associated with several pathologies including chronic respiratory diseases and cancer. In addition, exposure to cigarette smoke is correlated with impaired wound healing, where a significant decrease in ...
    • A Novel In Vivo Model to Study Impaired Tissue Regeneration Mediated by Cigarette Smoke 

      Alvarez, Marjorie; Chávez, Myra N.; Calorio Miranda, Miguel; Aedo, Geraldine; Allende Connelly, Miguel; Egaña, José T. (Nature Publishing Group, 2018)
      © 2018, The Author(s). Cigarette smoke is associated with several pathologies including chronic respiratory diseases and cancer. In addition, exposure to cigarette smoke is correlated with impaired wound healing, where a ...
    • Antiangiogenic, antimigratory and antiinflammatory effects of 2-methoxyestradiol in zebrafish larvae 

      Quezada, Marisol; Alvarez, Marjorie; Peña, Oscar A.; Henríquez, Soledad; Alençon, Claudia A. d'; Lange, Soledad; Oliva, Barbara; Owen, Gareth I.; Allende Connelly, Miguel (Elsevier, 2012-11-07)
      2-Methoxyestradiol (2ME), an endogenous metabolite of 17β-estradiol, has been previously reported to possess antiangiogenic and antitumor properties. Herein, we demonstrate that the effects of this antiangiogenic steroid ...
    • Generation of Viable Plant-Vertebrate Chimeras 

      Alvarez, Marjorie; Reynaert, Nicole; Chávez, Myra N.; Aedo, Geraldine; Araya, Francisco; Hopfner, Úrsula; Fernández Hidalgo, Juan; Allende Connelly, Miguel; Egaña, José T. (Public Library Science, 2015)
      The extreme dependence on external oxygen supply observed in animals causes major clinical problems and several diseases are related to low oxygen tension in tissues. The vast majority of the animals do not produce oxygen ...
    • Independent Anti-Angiogenic Capacities of Coagulation Factors X and Xa 

      Lange, Soledad; Gonzalez, Ibeth; Pinto, Mauricio P.; Arce, Maximiliano; Valenzuela, Rodrigo; Aranda, Evelyn; Elliot, Matias; Alvarez, Marjorie; Henriquez, Soledad; Velasquez, Ethel V.; Orge, Felipe; Oliva, Barbara; Gonzalez, Pamela; Villalon, Manuel; Cautivo, Kelly M.; (Wiley-Liss Inc., 2014)
      Knockout models have shown that the coagulation system has a role in vascular development and angiogenesis. Herein, we report for the first time that zymogen FX and its active form (FXa) possess anti-angiogenic properties. ...