Browsing by Author "7a356fb8-b24f-4f3d-8596-10269fa429c7"

Now showing items 1-4 of 4

    • Calcium mediates the activation of the inhibitory current induced by odorants in toad olfactory receptor neurons 
      Morales, Bernardo; Madrid, Rodolfo; Bacigalupo Vicuña, Juan (1997)
      In toad olfactory neurons, a putrid odorant mixture inducing inhibitory responses increases Ca2+-activated K+ conductance, developing a hyperpolarizing receptor potential. Removal of extracellular Ca2+ or exposure to ...
    • Non-conventional axonal organelles control TRPM8 ion channel trafficking and peripheral cold sensing 
      Cornejo, Víctor Hugo; González, Carolina; Campos, Matías; Vargas Saturno, Leslie; Juricic, María de los Ángeles; Miserey Lenkei, Stéphanie; Pertusa, María; Madrid, Rodolfo; Couve, Andrés (Cell Press, 2020)
      TRPM8 is the main ion channel responsible for cold transduction in the somatosensory system. Nerve terminal availability of TRPM8 determines cold sensitivity, but how axonal secretory organelles control channel delivery ...
    • Targeted overexpression of tumor necrosis factor-a increases cyclin-dependent kinase 5 activity and ... 
      Rozas, Pablo; Lazcano, Pablo; Piña, Ricardo; Cho, A.; Terse, Anita; Pertusa, María; Madrid, Rodolfo; González Billault, Christian; Kulkarni, Ashok B.; Utreras Puratich, Elías (Lippincott Williams & Wilkins, 2016)
      We reported earlier that TNF-alpha, a proinflammatory cytokine implicated in many inflammatory disorders causing orofacial pain, increases the activity of Cdk5, a key kinase involved in brain development and function and ...
    • Tonic and phasic receptor neurons in the vertebrate olfactory epithelium 
      Madrid, Rodolfo; Sanhueza, Magdalena; Alvarez, Osvaldo; Bacigalupo Vicuña, Juan (Biophysical Society, 2003)
      Olfactory receptor neurons (ORNs) respond to odorants with characteristic patterns of action potentials that are relevant for odor coding. Prolonged odorant exposures revealed three populations of dissociated toad ORNs, ...