Browsing by Author "8653fa33-9788-4886-9a34-f1dba476f494"

Now showing items 1-5 of 5

    • Crosstalk between RNA metabolism and cellular stress responses during Zika virus replication 
      Oyarzún Arrau, Aarón; Alonso-Palomares, Luis; Valiente Echeverría, Fernando; Osorio Olivares, Fabiola; Soto Rifo, Ricardo (MDPI, 2020)
      Zika virus (ZIKV) is a mosquito-borne virus associated with neurological disorders such as Guillain-Barré syndrome and microcephaly. In humans, ZIKV is able to replicate in cell types from di erent tissues including ...
    • Dopamine Receptor D3 Signaling on CD4(+) T Cells Favors Th1-and Th17-Mediated Immunity 
      Contreras, Francisco; Prado, Carolina; González, Hugo; Franz, Dafne; Osorio Barrios, Francisco; Osorio Olivares, Fabiola; Ugalde, Valentina; López, Ernesto; Elgueta, Daniela; Figueroa, Alicia; Lladser, Álvaro; Pacheco, Rodrigo (Amer Assoc Immunologists, 2016)
      Dopamine receptor D3 (DRD3) expressed on CD4(+) T cells is required to promote neuroinflammation in a murine model of Parkinson's disease. However, how DRD3 signaling affects T cell-mediated immunity remains unknown. In ...
    • Function in the development of neurodegenerative diseases 
      García González, Paulina; Cabral Miranda, Felipe; Hetz Flores, Claudio; Osorio Olivares, Fabiola (Frontiers Media S.A., 2018)
      Copyright © 2018 García-González, Cabral-Miranda, Hetz and Osorio. Emerging evidence suggests that the immune and nervous systems are in close interaction in health and disease conditions. Protein aggregation and proteostasis ...
    • Regulated Inositol Requiring Enzyme 1 dependent mRNA decay sets the threshold for dendritic cell survival 
      Tavernier, Simon J.; Osorio Olivares, Fabiola; Vandersarren, Lana; Vetters, Jessica; Vanlangenakke, Nele; Van Isterdael, Gert; Vergote, Karl; De Rycke, Riet; Parthoens, Eef; van de Laar, Lianne; Iwawaki, Takao; Valle, Juan R. del; Hu, Chih-Chi Andrew; Lambrecht, Bart N.; Janssens, Sophie (Nature Publishing Group, 2017)
      The IRE1/XBP1 signaling pathway is part of a cellular program that protects from endoplasmic reticulum (ER) stress, but also controls development and survival of immune cells. Loss of XBP1 in splenic type 1 conventional ...
    • The Unfolded protein response in immune cells as an emerging regulator of neuroinflammation 
      Fernández Quezada, Dominique; Geisse Anguita, Antonia; Bernales Schnettler, José Ignacio; Lira, Alonso; Osorio Olivares, Fabiola (Frontiers Media, 2021)
      Immune surveillance is an essential process that safeguards the homeostasis of a healthy brain. Among the increasing diversity of immune cells present in the central nervous system (CNS), microglia have emerged as a prominent ...