Browsing by Author "876a6e0b-3c18-4b04-a6e2-1f3be6705fdd"

Now showing items 1-4 of 4

    • A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis 
      Díaz Jiménez, David; Núñez, Lucía; Fuente, Marjorie de la; Dubois Camacho, Karen; Sepulveda, Hugo; Montecino, Martin; Torres Riquelme, Alejandro; García González, Paulina; Chnaiderman Figueroa, Jonás; Vossenkamper, Anna; MacDonald, Thomas T.; Simian, Daniela; González Burgos, María Julieta; Cidlowski, John A.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Nature Publishing Group, 2017)
      The ST2/IL33 signalling pathway has been associated with ulcerative colitis (UC). ST2, encoded by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and as a soluble receptor (sST2) ...
    • Epigenetic signatures at the RUNX2-P1 and Sp7 gene promoters control osteogenic lineage commitment of ... 
      Sepulveda, Hugo; Aguilar, Rodrigo; Prieto, Catalina P.; Bustos, Francisco; Aedo Monsalve, Sócrates; Lattus Olmos, José; Van Zundert, Brigitte; Palma, Verónica; Montecino, Martín (Wiley, 2017)
      Wharton's Jelly mesenchymal stem cells (WJ-MSCs) are an attractive potential source of multipotent stem cells for bone tissue replacement therapies. However, the molecular mechanisms involved in their osteogenic conversion ...
    • Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and ... 
      Araya López, Héctor; Sepulveda, Hugo; Lizama, Carlos O.; Vega Villa, Oscar; Jerez, Sofia; Briceño, Pedro F.; Thaler, Roman; Riester, Scott M.; Antonelli Anativia, Marcelo; Salazar Onfray, Flavio; Rodríguez Vives, Juan Pablo; Moreno, Ricardo D.; Montecino, Martín; Charbonneau, Martine; Dubois, Claire; Galindo Díaz, Mario; Stein, Gary; van Wijnen, Andre (Wiley-Liss Inc., 2018)
      Osteoblast differentiation is controlled by transcription factor RUNX2 which temporally activates or represses several bone-related genes, including those encoding extracellular matrix proteins or factors that control ...
    • Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 ... 
      Rojas, Adriana; Sepúlveda, Hugo; Henríquez, Berta; Aguilar, Rodrigo; Opazo, Tatiana; Nardocci, Gino; Bustos, Fernando; Lian, Jane B.; Stein, Janet L.; Stein, Gary S.; van Zundert, Brigitte; van Wijnen, Andre J.; Allende Connelly, Miguel; Montecino, Martín (Wiley, 2019)
      Expression of Runx2/p57 is a hallmark of the osteoblast-lineage identity. Although several regulators that control the expression of Runx2/p57 during osteoblast-lineage commitment have been identified, the epigenetic ...