Now showing items 1-15 of 15

    • A decade of HAART in Latin America: Long term outcomes among the first wave of HIV patients to receive combination therapy 

      Wolff Reyes, Marcelo; Giganti, Mark J.; Cortés Moncada, Claudia; Cahn, Pedro; Grinsztejn, Beatriz; Pape, Jean W.; Padgett, Denis; Sierra Madero, Juan; Gotuzzo, Eduardo; Duda, Stephany N.; McGowan, Catherine C.; Shepherd, Bryan E. (Public Library Science, 2017)
      Background In Latin America, the first wave of HIV-infected patients initiated highly active antiretroviral therapy (HAART) 10 or more years ago. Characterizing their treatment experience and corresponding outcomes across ...
    • Assessing the HIV Care Continuum in Latin America: progress in clinical retention, cART use and viral suppression 

      Rebeiro, Peter F.; César, Carina; Shepherd, Bryan E.; De Boni, Raquel B.; Cortés Moncada, Claudia; Rodríguez, Fernanda (Int Aids Society, 2016)
      Introduction: We assessed trends in HIV Care Continuum outcomes associated with delayed disease progression and reduced transmission within a large Latin American cohort over a decade: clinical retention, combination ...
    • Cancer in HIV-infected persons from the caribbean, central and South America 

      Fink, Valeria I.; Shepherd, Bryan E.; Cesar, Carina; Krolewiecki, Alejandro; Wehbe, Firas; Cortés, Claudia P.; Ramírez, Brenda Crabtree; Padgett, Denis; Shafaee, Maryam; Schechter, Mauro; Gotuzzo, Eduardo; Bacon, Melanie; McGowan, Catherine C.; Cahn, Pedro; Masys, Daniel (2011)
      Background: HIV-infected individuals have heightened cancer risk. With the advent of highly active antiretroviral therapy (HAART), the frequency of some AIDS-defining cancers (ADC) has decreased although certain non-AIDS-defining ...
    • CD4 response up to 5 years after combination antiretroviral therapy in human immunodeficiency virus-infected patients in Latin America and the Caribbean 

      Luz, Paula M.; Belaunzarán Zamudio, Pablo; Crabtree Ramírez, Brenda; Caro Vega, Yanink; Hoces, Daniel; Rebeiro, Peter F.; Blevins, Meridith; Pape, Jean W.; Cortés Moncada, Claudia; Padgett, Denis; Cahn, Pedro; Veloso, Valdilea G.; McGowan, Catherine C.; Grinsztejn, Beatriz; Shepherd, Bryan E. (Oxford University Press, 2015)
      We describe CD4 counts at 6-month intervals for 5 years after combination antiretroviral therapy initiation among 12 879 antiretroviral-naive human immunodeficiency virusinfected adults from Latin America and the Caribbean. ...
    • Cross-sectional analysis of late HARRT initiation in Latin America and the Caribbean: Late testers and late presenters 

      Crabtree Ramírez, Brenda; Caro Vega, Yanink; Shepherd, Bryan E.; Wehbe, Firas; Cesar, Carina; Cortés, Claudia; Padgett, Denis; Koenig, Serena; Gotuzzo, Eduardo; Cahn, Pedro; McGowan, Catherine C.; Masys, Daniel; Sierra Madero, Juan Juan; The CCASAnet Team, (2011)
      Background: Starting HAART in a very advanced stage of disease is assumed to be the most prevalent form of initiation in HIV-infected subjects in developing countries. Data from Latin America and the Caribbean is still ...
    • Durability of efavirenz compared with boosted protease inhibitor based regimens in antiretroviral naive patients in the Caribbean and Central and South America 

      Caro Vega, Yanink; Belaunzaran Zamudio, Pablo F.; Crabtree Ramírez, Brenda E.; Shepherd, Bryan E.; Grinsztejn, Beatriz; Wolff Reyes, Marcelo; Pape, Jean W.; Padgett, Denis; Gotuzzo, Eduardo; McGowan, Catherine C.; Sierra Madero, Juan G. (Oxford University Press, 2018)
      Background. Efavirenz (EFV) and boosted protease inhibitors (bPIs) are still the preferred options for firstline antiretroviral regimens (firstline ART) in Latin America and have comparable short-term efficacy. We assessed ...
    • Early retention in care neither mediates nor modifies the effect of sex and sexual mode of HIV acquisition on HIV survival in the Americas 

      Coelho, Lara; Rebeiro, Peter F.; Castilho, Jessica L.; Caro Veja, Yanink; Mejía, Fernando A.; César, Carina; Cortés Moncada, Claudia; Padgett, Denis; McGowan, Catherine C.; Veloso, Valdilea G.; Sterling, Timothy R.; Grinsztejn, Beatriz; Shepherd, Bryan E.; Luz, Paula M. (Mary Ann Liebert, 2018)
      Early retention in care, sex, and sexual mode of HIV acquisition has been associated with mortality risk among persons living with HIV (PLWH). We assessed whether early retention in care mediates or modifies the association ...
    • Health outcomes among HIV-positive Latinos initiating antiretroviral therapy in North America versus Central and South America 

      Cesar, Carina; Koethe, Jonh R.; Giganti, Mark J.; Rebeiro, Peter; Althoff, Keri N.; Napravnik, Sonia; Mayor, Ángel; Grinsztejn, Beatriz; Wolff Reyes, Marcelo; Padgett, Denis; Sierra Madero, Juan Juan; Gotuzzo, Eduardo; Sterling, Timothy R.; Willig, James; Levison, Julie; Kitahata, Mari; Rodríguez Barradas, María; Moore, Richard D.; McGowan, Catherine; Shepherd, Bryan E.; Cahn, Pedro (Int Aids Society, 2016)
      Introduction: Latinos living with HIV in the Americas share a common ethnic and cultural heritage. In North America, Latinos have a relatively high rate of new HIV infections but lower rates of engagement at all stages of ...
    • Incidence of virological failure and major regimen change of initial combination antiretroviral therapy in the Latin America and the Caribbean: An observational cohort study 

      Array, Array; Cesar, Carina; Jenkins, Cathy A.; Shepherd, Bryan E.; Padgett, Denis; Mejía, Fernando; Ribeiro, Sayonara Rocha; Cortés Moncada, Claudia; Pape, Jean W.; Madero, Juan Sierra; Fink, Valeria; Sued, Omar; McGowan, Catherine; Cahn, Pedro; Grinsztejn, Beatriz; Reyes, (Elsevier Ltd, 2015)
      © 2015 Elsevier Ltd. Background: Access to combination antiretroviral therapy (ART) is expanding in Latin America (Mexico, Central America, and South America) and the Caribbean. We assessed the incidence of and factors ...
    • Is substance use associated with HIV cascade outcomes in Latin America? 

      De Boni, Raquel; Peratikos, Meridith; Shepherd, Bryan; Grinsztejn, Beatriz; Cortés, Claudia; Padgett, Denis; Gotuzzo, Eduardo; Belaunzarán-Zamudio, Pablo; Rebeiro, Peter; Duda, Stephany; McGowan, Catherine (Public Library of Science, 2018)
      The HIV care cascade has improved in Latin America over the last decade. However, the influence of alcohol and noninjected drug use (NIDU) on cascade outcomes is mostly unknown. This study estimated the association of ...
    • Monitoring of HIV treatment in seven countries in the WHO region of the Americas Suivi du traitement du VIH dans sept pays de la Région OMS des Amériques Monitoreo del tratamiento del VIH en siete paises de la Region de las Americas de la OMS 

      Belaunzarán Zamudio, Pablo; Caro Vega, Yanink; Shepherd, Bryan E.; Crabtree Ramírez, Brenda; Luz, Paula M.; Grinsztejn, Beatriz; Cesar, Carina; Cahn, Pedro; Cortés, Claudia; Wolff Reyes, Marcelo; Pape, Jean W.; Padgett, Denis; Gotuzzo, Eduardo; McGowan, Catherine (World Health Organization, 2015)
      © 2015, World Health Organization. All Rights Reserved. Objective To determine the prevalence of adequate monitoring and the costs of measuring CD4+ T-lymphocytes (CD4+ cell) and human immunodeficiency virus (HIV) viral ...
    • Mortality during the first year of potent antiretroviral therapy in HIV-1-infected patients in 7 sites throughout latin America and the caribbean 

      Tuboi, Suely H.; Schechter, Mauro; McGowan, Catherine C.; Cesar, Carina; Krolewiecki, Alejandro; Cahn, Pedro; Wolff Reyes, Marcelo; Pape, Jean W.; Padgett, Denis; Madero, Juan Sierra; Gotuzzo, Eduardo; Masys, Daniel R.; Shepherd, Bryan E. (Lippincott Williams and Wilkins, 2009)
      BACKGROUND:: Although nearly 2 million people live with HIV in Latin America and the Caribbean, mortality rates after initiation of highly active antiretroviral therapy (HAART) have not been well described. METHODS:: Five ...
    • Rates and reasons for early change of first HAART in HIV-1-infected patients in 7 sites throughout the Caribbean and Latin America 

      Cesar, Carina; Shepherd, Bryan E.; Krolewiecki, Alejandro J.; Fink, Valeria I.; Schechter, Mauro; Tuboi, Suely H.; Wolff Reyes, Marcelo; Pape, Jean W.; Leger, Paul; Padgett, Denis; Madero, Juan Sierra; Gotuzzo, Eduardo; Sued, Omar; Mcgowan, Catherine C.; Masys, Daniel R.; Cah (2010)
      Background: HAART rollout in Latin America and the Caribbean has increased from approximately 210,000 in 2003 to 390,000 patients in 2007, covering 62% (51%-70%) of eligible patients, with considerable variation among ...
    • Time to HAART initiation after diagnosis and treatment of opportunistic infections in patients with AIDS in Latin America 

      Crabtree Ramírez, Brenda; Caro Vega, Yanink; Shepherd, Bryan E.; Grinsztejn, V; Grinsztejn, Beatriz; Wolff Reyes, Marcelo; Cortés Moncada, Claudia; Padgett, Denis; Carriquiry, Gabriela; Fink, Valeria; Jayathilake, Karu; Person, Anna K.; McGowan, Catherine; Sierra Madero, Juan (Public Library Science, 2016)
      Background Since 2009, earlier initiation of highly active antiretroviral therapy (HAART) after an opportunistic infection (OI) has been recommended based on lower risks of death and AIDS-related progression found in ...
    • Use of third line antiretroviral therapy in Latin America 

      Cesar, Carina; Shepherd, Bryan E.; Jenkins, Cathy A.; Ghidinelli, Massimo; Castro, Jose Luis; Veloso, Valdiléa Gonçalves; Cortés, Claudia P.; Padgett, Denis; Crabtree Ramírez, Brenda; Gotuzzo, Eduardo; Fink, Valeria; Duran, Adriana; Sued, Omar; McGowan, Catherine C. (Public Library of Science, 2014)
      © PLOS ONE 2014. Background: Access to highly active antiretroviral therapy (HAART) is expanding in Latin America. Many patients require second and third line therapy due to toxicity, tolerability, failure, or a combination ...