Now showing items 1-8 of 8

    • Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals 

      Ruiz Linares, Andrés; Adhikari, Kaustubh; Acuña Alonzo, Víctor; Quinto Sánchez, Mirsha; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Everardo, Paola; de Avila, Francisco; Gómez Valdés, Jorge; León Mimila, Paola; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Burley, Mari-Wyn; Konca, Esra; Zagonel de Oliveira, Marcelo; Veronez, Mauricio Roberto; Rubio Codina, Marta; Attanasio, Orazio; Gibbon, Sahra; Ray, Nicolás; Gallo, Carla; Poletti, Giovanni; Rosique, Javier; Schuler-Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria-Cátira; Canizales Quinteros, Samuel; Rothhammer, Francisco; Bedoya, Gabriel; Balding, David; González-José, Rolando (Public Library of Science, 2014)
      The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social ...
    • Facial Asymmetry and Genetic Ancestry in Latin American Admixed Populations 

      Quinto Sánchez, Mirsha; Adhikari, Kaustubh; Acuña Alonzo, Víctor; Cintas, Celia; Silva de Cerqueira, Caio Cesar; Ramallo, Virginia; Castillo, Lucia; Farrera, Arodi; Jaramillo, Claudia; Arias, Williams; Fuentes, Macarena; Everardo, Paola; Ávila, Francisco de; Gómez Valdés, Jorge; Hünemeier, Tabita; Gibbon, Shara; Gallo, Carla; Poletti, Giovanni; Rosique, Javier; Bortolini, María Cátira; Canizales Quinteros, Samuel; Rothhammer Engel, Francisco; Bedoya, Gabriel; Ruiz Linares, Andrés; González José, Rolando (Wuley Blackwell, 2015)
      Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants ...
    • Gene geography of Chile. Regional distribution of American, European and African genetic contributions Geografía génica de Chile. Distribución regional de los aportes genéticos Americanos, Europeos y Africanos 

      Fuentes, Macarena; Pulgar, Iván; Gallo, Carla; Bortolini, María Cátira; Canizales-Quinteros, Samuel; Bedoya, Gabriel; González-José, Rolando; Ruiz-Linares, Andrés; Rothhammer Engel, Francisco (Sociedad Medica de Santiago, 2014)
      Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ...
    • A genome-wide association study identifies multiple loci for variation in human ear morphology 

      Adhikari, Kaustubh; Reales, Guillermo; Smith, Andrew J.P.; Konka, Esra; Palmen, Jutta; Quinto Sánchez, Mirsha; Acuña Alonzo, Víctor; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Barquera Lozano, Rodrigo; Macín Pérez, Gastón; Gómez Valdés, Jorge; Villamil Ramírez, Hugo; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Gallo, Carla; Poletti, Giovanni; Schuler Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria Cátira; Canizales Quinteros, Samuel; Rothhammer Engel, Francisco; Bedoya, Gabriel; Calderón, Rosario; Rosique, Javier; Cheeseman, Michael; Bhutta, Mahmood F.; Humphries, Steve E.; González José, Rolando; Headon, Denis; Balding, David; Ruiz Linares, Andrés (Nature Publishing, 2015)
      Here we report a genome-wide association study for non-pathological pinna morphology in over 5,000 Latin Americans. We find genome-wide significant association at seven genomic regions affecting: lobe size and attachment, ...
    • Geografía génica de Chile. Distribución regional de los aportes genéticos americanos, europeos y africanos 

      Fuentes, Macarena; Pulgar, Iván; Gallo, Carla; Bortolini, María; Canizales Quinteros, Samuel; Bedoya, Gabriel; González José, Rolando; Ruiz Linares, Andrés; Rothhammer Engel, Francisco (Sociedad Médica de Santiago, 2014)
      Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ...
    • Geographic patterns of genome admixture in Latin American mestizos 

      Wang, Sijia; Ray, Nicolas; Rojas, Winston; Parra, Maria V.; Bedoya, Gabriel; Gallo, Carla; Poletti, Giovanni; Mazzotti, Guido; Hill, Kim; Hurtado, Ana M.; Camrena, Beatriz; Nicolini, Humberto; Klitz, William; Barrantes, Ramiro; Molina, Julio A.; Freimer, Nelson B.; Cátira Bortolini, María; Salzano, Francisco M.; Petzl-Erler, Maria L.; Tsuneto, Luiza T.; Dipierri, José E.; Alfaro, Emma L.; Bailliet, Graciela; Bianchi, Néstor O.; Llop Romero, Elena; Rothhammer Engel, Francisco; Excoffier, Laurent; Ruiz Linares, Andrés (PUBLIC LIBRARY SCIENCE, 2008-03)
      The large and diverse population of Latin America is potentially a powerful resource for elucidating the genetic basis of complex traits through admixture mapping. However, no genome-wide characterization of admixture ...
    • Implications of the admixture process in skin color molecular assessment 

      Silva de Cerqueira, Caio Cesar; Hünemeier, Tábita; Gómez Valdés, Jorge; Ramallo, Virginia; Volasko Krause, Carla Daiana; Leal Barbosa, Ana Angélica; Vargas Pinilla, Pedro; Ciconet Dornelles, Rodrigo; Longo, Danaé; Rothhammer Engel, Francisco; Bedoya, Gabriel; Canizales Quinteros, Samuel; Acuña Alonzo, Víctor; Gallo, Carla; Poletti, Giovanni; González José, Rolando; Mauro Salzano, Francisco; Callegari-Jacques, Sídia María; Schuler-Faccini, Lavínia; Ruiz Linares, Andrés; Bortolini, María Cátira (PLOS One, 2014)
      The understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes ...
    • Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile 

      Bermejo, Justo Lorenzo; Boekstegers, Félix; González Silos, Rosa; Marcelain Cubillos, Katherine; Báez Benavides, Pablo; Barahona Ponce, Carol; Mueller, Bettina; Ferreccio, Catterina; Koshiol, Jill; Fischer, Christine; Peil, Barbara; Sinsheimer, Janet; Fuentes Guajardo, Macarena; Barajas Barajas, Olga; González José, Rolando; Bedoya, Gabriel; Bortolini, María Catira; Canizales Quinteros, Samuel; Gallo, Carla; Ruiz Linares, Andrés; Rothhammer Engel, Francisco (Public Library Science, 2017)
      Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and ...