Browsing by Author "9ac098b0-96b9-4dec-a7ed-11b3cca067ab"

Now showing items 1-4 of 4

    • Chalcone-induced apoptosis through caspase-dependent intrinsic pathways in human hepatocellular carcinoma cells 
      Ramirez-Tagle, Rodrigo; Escobar, Carlos A.; Romero, Valentina; Montorfano, Ignacio; Armisén, Ricardo; Borgna, Vincenzo; Jeldes, Emanuel; Pizarro, Luis; Simon, Felipe; Echeverria, Cesar (MDPI AG, 2016)
      © 2016 by the authors; licensee MDPI, Basel, Switzerland. Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers worldwide. Chemoprevention of HCC can be achieved through the use of natural or synthetic ...
    • HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence ... 
      Villota, Claudio; Varas-Godoy, Manuel; Jeldes, Emanuel; Campos, América; Villegas, Jaime; Borgna, Vincenzo; Burzio, Luis O.; Burzio, Verónica A. (Impact Journals LLC, 2019)
      © Villota et al. Human and mouse cells display a differential expression pattern of a family of mitochondrial noncoding RNAs (ncmtRNAs), according to proliferative status. Normal proliferating and cancer cells express a ...
    • Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through ... 
      Lobos González, Lorena; Silva, Verónica; Araya, Mariela; Restovic, Franko; Echeñique, Javiera; Oliveira Cruz, Luciana; Fitzpatrick, Christopher; Briones, Macarena; Villegas, Jaime; Villota, Claudio; Vidaurre, Soledad; Borgna, Vincenzo; Socias, Miguel; Valenzuela, Sebastián; López, Constanza; Socias, Teresa; Varas, Manuel; Díaz, Jorge; Burzio, Luis O.; Burzio, Verónica A. (Impact Journals, 2016)
      We reported that knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, suggesting this approach for selective therapy against ...
    • The characterization of anti-T-cruzi activity relationships between ferrocenyl, cyrhetrenyl complexes and ... 
      Echeverría, César; Romero, Valentina; Arancibia, Rodrigo; Klahn, Hugo; Montorfano, Ignacio; Armisen Yáñez, Ricardo; Borgna, Vincenzo; Simon, Felipe; Ramírez Tagle, Rodrigo (Springer, 2016)
      Trypanosoma cruzi (T. cruzi) is the parasite that causes Chagas disease. Nifurtimox is the most used drug against the T. cruzi, this drug increases intermediaries nitro group, being mainly responsible for the high toxicity ...