Browsing by Author "XX568981"
Now showing items 1-20 of 109
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14-helical folding in a cyclobutane-containing beta-tetrapeptide
(AMER CHEMICAL SOC, 2004-07-23)The efficient synthesis of tetrapeptide 5 containing, in alternation, cyclobutane and beta-alanine residues is described. NMR experiments both at low temperature in CDCl3 and at 298 K in DMSOd(6) solutions show the ... -
A systematic study of antibacterial silver nanoparticles: efficiency, enhanced permeability, and cytotoxic effects
(Kluwer Academic Publishers, 2014)We report here a systematic study of the antibacterial behavior of silver nanoparticles coated with fatty acids (oleic: AgNP-O, linoleic: AgNP-L, and palmitic acids: AgNP-P) in water. We have found remarkable differences ... -
An intramolecular O-N migration reaction on gold surfaces: Toward the preparation of well-defined amyloid surfaces
(2009)Amyloids are a family of self-aggregating proteins implicated in various central nervous system disorders, including Alzheimer's disease (AD). It is thought that prefibrillar soluble forms of amyloid peptides, including ... -
Analysis of 25 C NBOMe in Seized Blotters by HPTLC and GC-MS
(Oxford University Press, 2016)© 2016 The Author 2016. Published by Oxford University Press.Use of unauthorized synthetic drugs is a serious, forensic, regulatory and public health issue. In this scenario, consumption of drug-impregnated blotters is ... -
Analysis of 25 C NBOMe in Seized Blotters by HPTLC and GC–MS
(Oxford University Press, 2016)Use of unauthorized synthetic drugs is a serious, forensic, regulatory and public health issue. In this scenario, consumption of drug-impregnated blotters is very frequent. For decades, blotters have been generally impregnated ... -
Antibacterial, kinetics and bacteriolytic properties of silver(I) pyridinedicarboxylate compounds
(Elsevier, 2014)Antibacterial properties of silver(I)-pyridinedicarboxylate compounds (with Pyridine-2,3-dicarboxylic(Lutidinic acid), pyridine-2,4-dicarboxylic (Quinolinic acid) and pyridine-2,5-dicarboxylic (Isocinchomeronic acid)) ... -
Assessment of polyaniline nanoparticles toxicity and teratogenicity in aquatic environment using Rhinella arenarum model
(Elsevier, 2015)With the rapid growth of nanotechnology and the applications of nanoparticles, environmental exposure to these particles is increasing. However, their impact in human and environmental health is not well studied. Anurans, ... -
Assessment of the Nature Interactions of beta-Amyloid Protein by a Nanoprobe Method
(Amer Chemical Soc, 2015)We present a method based on atomic force microscopy (AFM) to assess the work of adhesion between the interfaces of gold AFM tips functionalized with three peptides derived from beta-sheet breaker LPFFD [CLPFFD-NH2 (i(0)) ... -
Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice
(ELSEVIER, 2010)Gold nanoparticles (GNPs) offer a great promise in biomedicine. Currently, there is no data available regarding the accumulation of nanoparticles in vivo after repeated administration. The purpose of the present study ... -
Biocompatibilización de nanopartículas metálicas con copolimeros de quitosano
(Universidad de ChileCyberDocs, 2010)A pesar de los grandes adelantos científicos y tecnológicos, hoy en día aún hay diversas enfermedades que no poseen un método de diagnóstico y/o de tratamiento temprano y efectivo. Es por ello que actualmente se está ... -
Biomimetic quantum dot-labeled B16F10 murine melanoma cells as a tool to monitor early steps of lung metastasis by in vivo imaging
(NLM (Medline), 2018)Background: Numerous studies have proposed the use of fluorescent semiconductor nanoparticles or quantum dots (QDs) as novel tools to label cells and tumors. However, QD applications are limited by their toxicity in ... -
Capping biological quantum dots with the peptide CLPFFD to increase stability and to reduce effects on cell viability
(Springer, 2016)Highly fluorescent nanoparticles, or quantum dots, have multiple applications in biology and biomedicine; however, in most cases, it is necessary to functionalize them to enhance their biocompatibility and selectivity. ... -
Capping gold nanoparticles with modified chitosan polymers for biomedical applications
(American Scientific Publishers, 2013)With the purpose of obtaining stable and non-toxic nanocomposites with potential biomedical applications we coated gold nanoparticles (AuNP) with chitosan (CHI) and CHI grafted with poly(Nisopropilacrylamide) (PNIPAAm) and ... -
Carbon Nanotubes Electrochemistry Allows the In Situ Evaluation of the Effect of β-Sheet Breakers on the Aggregation Process of β-Amyloid
(2012)The inhibition of aggregation and disaggregation effect of a β-sheet breaker was evaluated by in situ electrochemistry of the Aβ 1-42 peptide. The exposition of 10tyr residue was followed using a carbon nanotubes modified ... -
Carboxymethylcellulose from bleached organosolv fibers of eucalyptus nitens: synthesis and physicochemical characterization
(Springer, 2018-05)The objective of the present study was to synthesize sodium carboxymethylcellulose from Eucalyptus nitens cellulose. The cellulose extraction was carried out in three stages. In the first stage, E. nitens wood was fractionated ... -
Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals: Role of oxidizable amino acid residues
(2013)Chemical and structural alterations to lysozyme (LYSO), glucose 6-phosphate dehydrogenase (G6PD), and bovine eye lens proteins (BLP) promoted by peroxyl radicals generated by the thermal decomposition of 2,2′-azobis(2- ... -
Chemical Modification of Lysozyme, Glucose 6‑Phosphate Dehydrogenase, and Bovine Eye Lens Proteins Induced by Peroxyl Radicals: Role of Oxidizable Amino Acid Residues
(2013)Chemical and structural alterations to lysozyme (LYSO), glucose 6-phosphate dehydrogenase (G6PD), and bovine eye lens proteins (BLP) promoted by peroxyl radicals generated by the thermal decomposition of 2,2′-azobis(2 ... -
CLPFFD-PEG functionalized NIR-absorbing hollow gold nanospheres and gold nanorods inhibit beta-amyloid aggregation
(Royal Soc Chemistry, 2018-04-28)Gold nanoparticles with specific optical properties in combination with the CLPFFD peptide that exhibits selectivity for beta-amyloid (A beta) aggregates are promising photothermal absorbers for application in Alzheimer's ... -
Conjugation of Kahalalide F with gold nanoparticles to enhance in vitro antitumoral activity
(2009)Two Cys-containing analogues of the anticancer drug Kahalalide F are synthesized and conjugated to 20 and 40 nm gold nanoparticles (GNPs). The resulting complexes are characterized by different analytical techniques to ...
