Now showing items 1-10 of 10

    • Herrera, Andrea; Muñoz Tapia, Patricia; Paris Pizarro, Irmgard; Díaz Véliz, Gabriela; Mora Gutiérrez, Sergio; Inzunza, José; Hultenby, Kjell; Cárdenas Matus, Julio; Jaña Prado, Fabián; Raisman Vozari, Rita; Gysling, Katia; Abarca, Jorge; Steinbusch, Harry; Segura Aguilar, Juan (Springer, 2016)
      L-Dopa continues to be the gold drug in Parkinson's disease ( PD) treatment from 1967. The failure to translate successful results from preclinical to clinical studies can be explained by the use of preclinical models which ...
    • Quinteros Muñoz, David; Sáez Briones, Patricio; Díaz Véliz, Emma; Mora Gutiérrez, Sergio; Rebolledo Fuentes, Marco; Cassels Niven, Bruce (AMER PSYCHOLOGICAL ASSOC, 2010-06-30)
      3,4-methylenedioxymethamphetamine (MDMA; “ecstasy”) is a psychoactive drug structurally related to other phenylisopropylamines acting as stimulants or hallucinogens in humans. Although MDMA has a pharmacological identity ...
    • Gargiulo, Augusto P. I.; Acuña, Andrés; Gargiulo, Mercedes M. L.; Gargiulo, Ángel J. M.; Gargiulo, Marcos C. J.; Baiardi, Gustavo C.; Mora Gutiérrez, Sergio; Lafuente, José Vicente; Romanowicz, Esteban; Landa, Adriana I.; Guevara, Manuel A.; Gargiulo, Pascual Ángel (Karger, 2020)
      Introduction: In recent years, an important number of studies have emphasized the psychopharmacological actions of cycloleucine (1-aminocyclopentanecarboxylic acid) acting on the NR1 subunit (glycine allosteric site) of ...
    • Mora Gutiérrez, Sergio; Dussaubat, Nelson; Díaz Véliz, Gabriela (1998)
      Several studies have demonstrated that the peptide LHRH can modify behavior in the male rat. Peripheral and intracerebral infusions of LHRH impair the acquisition of conditioned avoidance responses (CARs) and increase some ...
    • Díaz Véliz, Gabriela; Soto, Veronica; Dussaubat, Nelson; Mora Gutiérrez, Sergio (1989)
      The changes in the acquisition of conditioned avoidance responses (CARs) and the performance of some spontaneous behaviors were examined across the estrous cycle of female rats. CARs were facilitated during diestrus, ...
    • Díaz Véliz, Gabriela; Dussaubat, Nelson; Mora Gutiérrez, Sergio (1997)
      The present investigation was designed to explore the influence of estrous cycle phase, ovariectomy, and estradiol replacement on the behavioral effects of the 5-HT2 receptor antagonist, ketanserin. The parameters under ...
    • Mora Gutiérrez, Sergio; Díaz Véliz, Gabriela (Springer-Verlag, 1985)
      The influence of posttraining subcutaneous administration of luteinizing-hormone-releasing hormone (LHRH) was tested on the retention of either active or passive avoidance conditioning in male rats. Injection of LHRH ...
    • Herrera Soto, Andrea; Díaz Véliz, Gabriela; Mora Gutiérrez, Sergio; Muñoz, Patricia; Henny, Pablo; Steinbusch, Harry W. M.; Segura Aguilar, Juan (Springer, 2017)
      Dopamine oxidation in the pathway leading to neuromelanin formation generates the ortho-quinone aminochrome, which is potentially neurotoxic but normally rapidly converted by DT-diaphorase to nontoxic leukoaminochrome. ...
    • Díaz Véliz, Gabriela; Mora Gutiérrez, Sergio; Bianchi, Ricardo; Gargiulo, Pascual; Terán Calderón, Carolina; Gorena, Dorian; Lafuente-Sánchez, José; Escanero-Marcen, Jesús (2011)
      Objetivo. Evaluar y comparar la percepción que del ambiente educativo tienen los estudiantes de medicina de dos universidades iberoamericanas: Universidad de Chile (UCH) y Universidad Nacional de Cuyo (UNC), que desarrollan ...
    • García Rojo, Gonzalo; Fresno, Cristóbal; Vilches Peñaloza, Natalia; Díaz Véliz, Emma; Mora Gutiérrez, Sergio; Aguayo Abarca, Felipe; Pacheco Zapata, Aníbal; Parra Fiedler, Nicolás; Parra, Claudio; Rojas Domínguez, Paulina; Tejos Bravo, Macarena; Aliaga, Esteban; Fiedler Temer, Jenny (Oxford University Press, 2017-04-01)
      Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply ...