Now showing items 1-8 of 8

    • Miranda, Hugo F.; Sierralta, Fernando; Aranda, Nicolas; Poblete, Paula; Castillo, Rodrigo; Noriega, Viviana; Prieto, Juan (Elsevier, 2018-06)
      Background: Neuropathic pain, and subsequent hypernociception, can be induced in mice by paclitaxel (PTX) administration and partial sciatic nerve ligation (PSNL). Its pharmacotherapy has been a clinical challenge, due to ...
    • Miranda, Hugo F.; Noriega, Viviana; Prieto, Juan Carlos; Zanetta, Pilar; Castillo, Rodrigo; Aranda, Nicol as; Sierralta, Fernando (Nordic Association for the Publication of BCPT, 2016)
      Neuropathic pain is the result of injury to the nervous system, and different animal models have been established to meet the manifestations of neuropathy. The pharmacotherapy for neuropathic pain includes gabapentin and ...
    • Miranda, Hugo F.; Puig, Margarita M.; Dursteler, Christian; Prieto, Juan Carlos; Pinardi, Gianni (2007)
      The antinociceptive activity of dexketoprofen was studied in mice using the acetic acid writhing test (acute tonic pain), the tail flick test (acute phasic pain) and the formalin assay (inflammatory pain). Isobolographic ...
    • Prieto, Juan Carlos; Sanhueza, Consuelo; Martínez, Nicolás; Nazzal, Carolina; Corbalán, Ramón; Cavada Chacón, Gabriel; Lanas, Fernando; Bartolucci, Jorge; Campos, Pabla; Gatica, Mario; Gaete, Pablo; Bustos, Carlos; Araya, María Virginia; Cotoras, Juan Antonio; Bonacic, Fernan (Sociedad Medica de Santiago, 2008)
      Background: Primary angioplasty is considered the best reperfusion therapy in the treatment of ST-segment elevation myocardial infarction (STEMI). However, thrombolysis is the reperfusion method most commonly used, due to ...
    • Miranda, Hugo F.; Noriega, Viviana; Zanetta, Pilar; Prieto, Juan Carlos (Quintessence Publishing Co. Inc., 2013)
      © Quintessence. Aims: To evaluate the nature of the antinociceptive interaction of systemic administration of a combination of the anticonvulsant gabapentin with the antidepressant nortriptyline, by isobolographic analysis ...
    • Vargas, Claudio Gonzalez; Miranda, Hugo F.; Sierralta, Fernando; Noriega, Viviana; Prieto, Juan Carlos (Wiley-Liss Inc., 2019)
      Nonsteroidal anti-inflammatory drugs (NSAIDs) possess as primary action mechanism the inhibition of cyclooxygenases (COX-1, COX-2, and COX-3), thus producing a decreasing prostaglandin synthesis. This study was designed ...
    • Miranda, Hugo F.; Noriega, Viviana; Prieto, Juan Carlos (2012)
      In the treatment of acute and chronic pain the most frequently used drugs are nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., paracetamol; opioids, e.g., tramadol, and a group of drugs called coanalgesics or adjuvants ...
    • Kolls, Brad J.; Sapp, Shelly; Rockhold, Frank W.; Jordan, J. Dedrick; Dombrowski, Keith E.; Fowkes, F. Gerry R.; Mahaffey, Kenneth W.; Berger, Jeffrey S.; Katona, Brian G.; Blomster, Juuso I.; Norgren, Lars; Abramson, Beth L.; Leiva-Pons, Jose L.; Prieto, Juan Carlos; (NLM (Medline), 2019)
      Background and Purpose- Predictors of stroke and transient ischemic attack (TIA) in patients with peripheral artery disease (PAD) are poorly understood. The primary aims of this analysis were to (1) determine the incidence ...