Browsing by Author "a25ad1e6-63e0-4ac6-8a1c-e26412747a5a"
Now showing items 1-7 of 7
-
Varela, Nelson; Quiñones Sepúlveda, Luis; Stojanova, Jana; Garay, Joselyn; Cáceres, Dante; Cespedes, Silvia; Sasso, Jaime; Miranda, Carla (Elsevier, 2015-11)We tested the influence of four polymorphisms and gene duplication in CYP2D6 on in vivo enzyme activity in a Chilean mestizo population in order to identify the most relevant genetic profiles that account for observed ...
-
Galindo, Mario A.; Varela, Nelson; Espinoza, Ingrid; Toro, Gabriela Cecilia; Hellman, Ulf; Wernstedt, Christer; Galanti Garrone, Norbel (2004)Histones from the parasitic platyhelminthes, Echinococcus granulosus and Fasciola hepatica, were systematically characterized. Core histones H2A, H2B, H3 and H4, which were identified on the basis of amino acid sequencing ...
-
Lee, Kuen; Cáceres, Dante; Varela, Nelson; Csendes D, Atila; Ríos R, Horacio; Quiñones Sepúlveda, Luis (2006)Background: Gastric cancer (GaC) is the second cause of death by cancer in the world and one of the first causes in Chile. However, the burden of this disease shows remarkable worldwide variation probably explained by ...
-
San Martin, Inga A.; Varela, Nelson; Gaete, Marcia; Villegas, Karina; Osorio, Mariana; Tapia, Julio; Antonelli, Marcelo; Mancilla, Edna E.; Pereira, Barry P.; Nathan, Saminathan S.; Lian, Jane B.; Stein, Janet L.; Stein, Gary S.; Van Wijnen, Andre J.; Galindo, Mario A. (2009)Bone formation and osteoblast differentiation require the functional expression of the Runx2/Cbfβ heterodimeric transcription factor complex. Runx2 is also a suppressor of proliferation in osteoblasts by attenuating cell ...
-
Orellana, Myriam; Varela, Nelson; Guajardo, Viviana; Araya, Julia; Rodrigo Salinas, Ramón (2002)Cytochrome P450-dependent oxidation of lauric acid, p-nitrophenol and ethanol by liver microsomal fractions were studied in control rats and in animals given either ethanol, red wine, or alcohol-free red wine for 10 weeks. ...
-
Roco, Ángela; Cerda, Berta; Cayún, Juan Pablo; Lavanderos, Alejandra; Rubilar, Juan Carlos; Cerro, Roberto; Acevedo, Christian; Cáceres, Dante; Varela, Nelson; Quiñones, Luis A. (Sociedad Chilena de Pediatria, 2018)© 2018, Sociedad Chilena de Pediatria. All rights reserved. Cancer is the second leading cause of death in the world, causing 8.8 million deaths in 2015 according to the World Health Organization (WHO). Risk factors for ...
-
Orellana, Myriam; Rodrigo Salinas, Ramón; Varela, Nelson; Araya, Julia; Poniachik Teller, Jaime; Csendes Juhasz, Attila; Smok Sahid, Gladys; Videla Cabrera, Luis (2006)The aim of the present study was to test the hypothesis that induction of cytochrome P450 2E1 (CYP2E1) in the liver of patients with non-alcoholic fatty liver disease (NAFLD) is correlated both with the in vivo activity ...