Browsing by Author "a5f1c93a-2fef-4bcd-a2d3-2b827cfe8a41"

Now showing items 1-5 of 5

    • A CLCA regulatory protein present in the chemosensory cilia of olfactory sensory neurons induces a Ca2+ ... 
      Mura, Casilda V.; Delgado Arriagada, Ricardo; Delgado, María Graciela; Restrepo, Diego; Bacigalupo Vicuña, Juan (BIOMED Central Ltd., 2017)
      Background: CLCA is a family of metalloproteases that regulate Ca2+-activated Cl- fluxes in epithelial tissues. In HEK293 cells, CLCA1 promotes membrane expression of an endogenous Anoctamin 1 (ANO1, also termed ...
    • An in vitro method for studying subcellular rearrangements during cell polarization in Drosophila melanogaster ... 
      Edwards, Sandra Sofía; Delgado, María Graciela; Nader, Guilherme Pedreira de Freitas; Piel, Matthieu; Bellaïche, Yohanns; Lennon Duménil, Ana María; Glavic Maurer, Álvaro (Elsevier Ireland Ltd, 2018)
      © 2018Thanks to the power of Drosophila genetics, this animal model has been a precious tool for scientists to uncover key processes associated to innate immunity. The fly immune system relies on a population of macrophage-like ...
    • Chaski, a novel drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional ... 
      Delgado, María Graciela; Oliva, Carlos; López, Estefanía; Ibacache, Andrés; Galaz, Alex; Delgado, Ricardo; Barros, L. Felipe; Sierralta, Jimena (Nature Publishing Group, 2018)
      The intercellular transport of lactate is crucial for the astrocyte-to-neuron lactate shuttle (ANLS), a model of brain energetics according to which neurons are fueled by astrocytic lactate. In this study we show that the ...
    • Light-Induced Opening of the TRP Channel in Isolated Membrane Patches Excised from Photosensitive Microvilli ... 
      Delgado Arriagada, Ricardo; Delgado, María Graciela; Bastin Héline, Lucie; Glavic Maurer, Álvaro; O'Day, Peter M.; Bacigalupo Vicuña, Juan (Elsevier, 2019)
      Drosophila phototransduction occurs in light-sensitive microvilli arranged in a longitudinal structure of the photoreceptor, termed the rhabdomere. Rhodopsin (Rh), isomerized by light, couples to G-protein, which activates ...
    • Scaffolding proteins in highly purified rat olfactory cilia membranes 
      Saavedra, María Verónica; Smalla, Karl Heinz; Thomas, Ulrich; Sandoval, Soledad; Olavarria, Karel; Castillo, Karen; Delgado, María Graciela; Delgado, Ricardo; Gundelfinger, Eckart D.; Bacigalupo Vicuña, Juan; Wyneken, Ursula (2008)
      Odour-mediated signal transduction is a complex process that occurs in the cilia of olfactory sensory neurons. To gain insight in to the molecular organization of the odour transduction machinery, we developed a procedure ...