Browsing by Author "a7477b48-33df-429f-9a61-6a7139656aaa"

Now showing items 1-3 of 3

    • Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response 
      Díaz, María I.; Díaz, Paula; Castillo Bennett, Jimena; Urra, Hery; Ortiz, Rina; Contreras Orellana, Pamela; Hetz Flores, Claudio; Quest, Andrew F. G. (Springer Nature, 2020)
      Caveolin-1 (CAV1), is a broadly expressed, membrane-associated scaffolding protein that acts both, as a tumor suppressor and a promoter of metastasis, depending on the type of cancer and stage. CAV1 is downregulated in ...
    • Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma ... 
      Ortiz, Rina; Díaz Jara, Jorge; Díaz, Natalia; Lobos González, Lorena; Cárdenas, Areli; Contreras, Pamela; Díaz, María Inés; Otte, Ellen; Cooper- White, Justin; Torres Gómez, Vicente; Leyton Campos, Lisette; Quest, Andrew F. G. (Impact Journals LLC, 2016)
      Caveolin-1 (CAV1) is a scaffolding protein that plays a dual role in cancer. In advanced stages of this disease, CAV1 expression in tumor cells is associated with enhanced metastatic potential, while, at earlier stages, ...
    • Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells 
      Ortiz, Rina; Díaz, Jorge; Díaz Valdivia, Natalia; Martínez Meza, Samuel; Simón, Layla; Contreras Orellana, Pamela; Lobos González, Lorena; Guerrero, Simón; Leyton Campos, Lisette; Quest, Andrew F. G. (Elsevier, 2020)
      In advanced stages of cancer disease, caveolin-1 (CAV1) expression increases and correlates with increased migratory and invasive capacity of the respective tumor cells. Previous findings from our laboratory revealed that ...