Now showing items 1-4 of 4

    • ESR, electrochemical and ORAC studies of nitro compounds with potential antiprotozoal activity 

      Aravena, María C.; Figueroa, Roberto; Olea Azar, Claudio; Arán, Vicente J. (2010)
      Cyclic Voltammetry (CV) and electron spin resonance (ESR) techniques were used in the investigation of several potentially antiprotozoal nitro derivatives of dihydroquinoxaline and indazole. A self-protonation process ...
    • Evaluation of Antioxidant and Antitrypanosomal Properties of a Selected Series of Synthetic 3-Carboxamidocoumarins 

      Muñoz, Andrea; Fonseca, André; Matos, Maria J.; Uriarte, Eugenio; Santana, Lourdes; Borges, Fernanda; Figueroa, Roberto; Olea Azar, Claudio (Wiley-Blackwell, 2016)
      © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Oxidative stress is involved in several parasitic diseases such as Chagas. Agents able to selectively modulate biochemical processes involved in the disease represent ...
    • Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites 

      Fernández, Mariana; Rodríguez Arce, Esteban; Sarniguet, Cynthia; Morais, Tânia S.; Tomaz, Ana Isabel; Olea Azar, Claudio; Figueroa, Roberto; Maya Arango, Juan; Medeiros, Andrea; Comini, Marcelo; Garcia, M. Helena; Otero, Lucía; Gambino, Dinorah (Elsevier, 2015)
      Searching for new prospective antitrypanosomal agents, three novel Ru(II)-cyclopentadienyl compounds, [Ru(eta(5)-C5H5)(PPh3)L], with HL = bioactive 5-nitrofuryl containing thiosemicarbazones were synthesized and characterized ...
    • Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents 

      Vieites, Marisol; Otero, Lucía; Santos, Diego; Toloza, Jeannette; Figueroa, Roberto; Norambuena, Ester; Olea Azar, Claudio; Aguirre, Gabriela; Cerecetto, Hugo; González, Mercedes; Morello Casté, Antonio; Maya Arango, Juan; Garat, Beatriz; Gambino, Dinorah (ELSEVIER SCIENCE INC, 2008-05)
      In the search for new therapeutic tools against Chagas’ disease (American Trypanosomiasis) two series of new platinum(II) complexes with bioactive 5-nitrofuryl containing thiosemicarbazones as ligands were synthesized, ...