Browsing by Author "b4030e56-1850-4899-a1b9-f2b030f35798"

Now showing items 1-2 of 2

    • Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin ... 
      Cerda Cavieres, Christopher David; Quiroz, Gabriel; Iturriaga-Vásquez, Patricio; Rodríguez Lavado, Julio; Alarcón Espósito, Jazmín; Saitz Barría, Claudio; Pessoa Mahana, Carlos D.; Chung, Hery; Araya Maturana, Ramiro; Mella Raipán, Jaime A.; Cabezas, David; Ojeda Gómez, Claudia; Reyes Parada, Miguel; Pessoa Mahana, Hernán (MDPI, 2020)
      A series of 27 compounds of general structure 2,3-dihydro-benzo[1,4]oxazin-4-yl)-2-{4-[3-(1H-3indolyl)-propyl]-1-piperazinyl}-ethanamides, Series I: 7(a-o) and (2-{4-[3-(1H-3-indolyl)-propyl]-1-piperazinyl}-acetylamine)- ...
    • Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines ... 
      Rodríguez Lavado, Julio; Gallardo Garrido, Carlos; Mallea Catalán, Michael; Bustos, Víctor; Osorio, Rodrigo; Hödar Salazar, Martín; Chung, Hery; Araya Maturana, Ramiro; Lorca, Marcos; Pessoa Mahana, C. David; Mella Raipán, Jaime; Saitz Barría, Claudio; Jaque Olmedo, Pablo; Reyes Parada, Miguel; Iturriaga-Vásquez, Patricio; Pessoa Mahana, Hernán (Elsevier, 2020)
      During the last decade, the one drug-one target strategy has resulted to be inefficient in facing diseases with complex ethiology like Alzheimer's disease and many others. In this context, the multitarget paradigm has ...