Now showing items 1-5 of 5

    • Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials 

      Kasenda, Benjamín; von Elm, Erik; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari; Neumann, Ignacio; Carrasco Labra, Raúl; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martín A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Public Library Science, 2016)
      Background Little is known about publication agreements between industry and academic investigators in trial protocols and the consistency of these agreements with corresponding statements in publications. We aimed to ...
    • Completion and Publication Rates of Randomized Controlled Trials in Surgery An Empirical Study 

      Rosenthal, Rachel; Kasenda, Benjamin; Dell-Kuster, Salome; Elm, Erik von; You, John; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Sohail, Mulla; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Olu, Kelechi K.; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Bradley C., Johnston; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Lippicott Williams & Wilkins, 2015)
      Objective: To investigate the prevalence of discontinuation and nonpublication of surgical versus medical randomized controlled trials (RCTs) and to explore risk factors for discontinuation and nonpublication of surgical ...
    • Microbial preparations (probiotics) for the prevention of Clostridium difficile infection in adults and children: an individual patient data meta-analysis of 6,851 participants 

      Johnston, Bradley C.; Lytvyn, Lyubov; Calvin, Ka-Fung Lo; Allen, Stephen; Wang, Duolao; Szajewska, Hania; Miller, Mark; Ehrhardt, Stephan; Sampalis, John; Duman, Deniz; Pozzoni, Pietro; Colli, Agostino; Lonnermark, Elisabet; Selinger, Christian; Wong, Samford; Plummer, Susan; Hickson, Mary; Pancheva, Ruzha; Hirsch Birn, Sandra; Klarin, Bengt; Goldenberg, Joshua; Wang, Li; Mbuagbaw, Lawrence; Foster, Gary; Maw, Anna; Sadeghirad, Behnam; Thabane, Lehana; Mertz, Dominik (Cambridge University Press, 2018-07)
      OBJECTIVE. To determine whether probiotic prophylaxes reduce the odds of Clostridium difficile infection (CDI) in adults and children. DESIGN. Individual participant data (IPD) meta-analysis of randomized controlled ...
    • Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study 

      Schandelmaier, Stefan; Elm, Erik von; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Lamontagne, Francois; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Sun, Xin; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Cook, Deborah J.; Meade, Maureen O.; Bucher, Heiner C.; Kasenda, Benjamin; Briel, Matthias (Lippicott Williams & Wilkins, 2016)
      Objectives: Randomized clinical trials that enroll patients in critical or emergency care (acute care) setting are challenging because of narrow time windows for recruitment and the inability of many patients to provide ...
    • Prevalence, Characteristics, and Publication of Discontinued Randomized Trials 

      Kasenda, Benjamin; Von Elm, Erik; You, John; Blümle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Schandelmaier, Stefan; Xin, Sun; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (American Medical Association., 2014)
      IMPORTANCE The discontinuation of randomized clinical trials (RCTs) raises ethical concerns and often wastes scarce research resources. The epidemiology of discontinued RCTs, however, remains unclear. OBJECTIVES To ...