Now showing items 1-8 of 8

    • Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials 

      Kasenda, Benjamín; von Elm, Erik; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari; Neumann, Ignacio; Carrasco Labra, Raúl; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martín A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Public Library Science, 2016)
      Background Little is known about publication agreements between industry and academic investigators in trial protocols and the consistency of these agreements with corresponding statements in publications. We aimed to ...
    • Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review abstracts 

      Agarwal, Arnav; Johnston, Bradley C.; Vernooij, Robin W.M.; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie A; Sun, Xin; Briel, Matthias; Busse, Jason W.; Ebrahim, Shanil; Granados, Carlos E.; Iorio, Alfonso; Irfan, Affan; Martínez G (Elsevier USA, 2017)
      © 2016 Elsevier Inc. Objectives Explicit reporting of absolute measures is important to ensure treatment effects are correctly interpreted. We examined the extent to which authors report absolute effects for patient-important ...
    • Completion and Publication Rates of Randomized Controlled Trials in Surgery An Empirical Study 

      Rosenthal, Rachel; Kasenda, Benjamin; Dell-Kuster, Salome; Elm, Erik von; You, John; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Sohail, Mulla; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Olu, Kelechi K.; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Bradley C., Johnston; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Lippicott Williams & Wilkins, 2015)
      Objective: To investigate the prevalence of discontinuation and nonpublication of surgical versus medical randomized controlled trials (RCTs) and to explore risk factors for discontinuation and nonpublication of surgical ...
    • The GRADE approach is reproducible in assessing the quality of evidence of quantitative evidence syntheses 

      Mustafa, Reem A.; Santesso, Nancy; Brozek, Jan; Akl, Elie A.; Walter, Stephen D.; Norman, Geoff; Kulasegaram, Mahan; Christensen, Robin; Guyatt, Gordon H.; Falck Ytter, Yngve; Chang, Stephanie; Hassan Murad, Mohammad; Vist, Gunn E.; Lasserson, Toby; Gartlehner, Gerald; Shukla, Vijay; Sun, Xin; Whittington, Craig; Post, Piet N.; Lang, Eddy; Thaler, Kylie; Kunnamo, Ilkka; Alenius, Heidi; Meerpohl, Joerg J.; Alba, Ana C.; Nevis, Immaculate F.; Gentles, Stephen; Ethier, Marie Chantal; Carrasco Labra, Raúl; Khatib, Rasha; Nesrallah, Gihad; Kroft, Jamie; Selk, Amanda; Brignardello Petersen, Romina; Schünemann, Holger J. (Elsevier, 2013)
      Objective: We evaluated the inter-rater reliability (IRR) of assessing the quality of evidence (QoE) using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. Study Design and Setting: ...
    • Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study 

      Schandelmaier, Stefan; Elm, Erik von; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Lamontagne, Francois; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Sun, Xin; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Cook, Deborah J.; Meade, Maureen O.; Bucher, Heiner C.; Kasenda, Benjamin; Briel, Matthias (Lippicott Williams & Wilkins, 2016)
      Objectives: Randomized clinical trials that enroll patients in critical or emergency care (acute care) setting are challenging because of narrow time windows for recruitment and the inability of many patients to provide ...
    • Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide 

      Akl, Elie A; Shawwa, Khaled; Kahale, Lara A.; Agoritsas, Thomas; Brignardello Petersen, Romina; Busse, Jason W.; Carrasco Labra, Alonso; Ebrahim, Shanil; Johnston, Bradley C.; Neumann, Ignacio; Solà, Iván; Sun, Xin; Vandvik, Per; Zhang, Yuqing; Alonso Coello, Pablo; Guyatt, Gordon H. (BMJ Publishing Group, 2015)
      Objectives We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the ...
    • Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey 

      Akl, Elie A.; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Johnston, Bradley C.; Sun, Xin; Briel, Matthias; Busse, Jason W.; Ebrahim, Shanil; Granados, Carlos E.; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem A.; Ramírez Morera, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea Juliana; Tikkinen, Kari A. O.; Vandvik, Per O.; Vernooij, Robin W. M.; Zazueta, Oscar E.; Zhou, Qi; Guyatt, Gordon H.; Alonso Coello, Pablo (BMJ, 2015)
      Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias. Methods: We searched MEDLINE and the Cochrane ...
    • Systematic reviews experience major limitations in reporting absolute effects 

      Alonso Coello, Pablo; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Vernooij, Robin; Johnston, Brad; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramírez Morers, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea; Tikkinen, Kari; Vandvik, Per; Zazueta, Oscar; Zhang, Yuqing; Zhou, Qi; Schünemann, Holger; Guyatt, Gordon H. (Elsevier, 2016)
      Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain ...