Browsing by Author "c2d107e3-c912-4d0f-a365-2946bba5a0d2"

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    • Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome ... 
      Kim, Soo Young; Zhang, Xin; Schiattarella, Gabriele G.; Altamirano, Francisco; Ramos, Thais; French, Kristin M.; Jiang, Nan; Szweda, Pamela A.; Evers, Bret M.; May, Herman; Luo, Xiang; Li, Hongliang; Szweda, Luke; Maracajá Coutinho, Vinicius; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Lippincott Williams & Wilkins, 2020)
      BACKGROUND: BET (bromodomain and extraterminal) epigenetic reader proteins, in particular BRD4 (bromodomain-containing protein 4), have emerged as potential therapeutic targets in a number of pathological conditions, ...
    • Nitrosative stress drives heart failure with preserved ejection fraction 
      Schiattarella, Gabriele G.; Altamirano, Francisco; Tong, Dan; French, Kristin M.; Villalobos, Elisa; Kim, Soo Young; Luo, Xiang; Jiang, Nan; May, Herman I.; Wang, Zhao V.; Hill, Theodore M.; Mammen, Pradeep; Huang, Jian; Lee, Dong I.; Hahn, Virginia; Sharma, Kavita; Kass, David A.; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Nature Publishing Group, 2019)
      Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with high morbidity and mortality for which there are no evidence-based therapies. Here we report that concomitant metabolic and hypertensive ...