Browsing by Author "c3a80c57-94d0-460d-841d-a5b2da51db6c"
Now showing items 1-13 of 13
-
Vergara Montecinos, Cecilia; Ramirez, Beatriz; Behrens Pellegrino, María Isabel (1993)A low conductance calcium‐activated K+ channel is thought to regulate the rate of firing of several excitable cells. In skeletal muscle the expression of this channel is under nerve control. Previously, we reported that ...
-
Effects of ATP, Mg2+, and redox agents on the Ca2+ dependence of RyR channels from rat brain cortex Bull Simpfendorfer, Ricardo; Finkelstein, José Pablo; Humeres, Alexis; Behrens Pellegrino, María Isabel; Hidalgo Tapia, María Cecilia (AMER PHYSIOLOGICAL SOC, 2007-07)Despite their relevance for neuronal Ca2+-induced Ca2+ release (CICR), activation by Ca2+ of ryanodine receptor (RyR) channels of brain endoplasmic reticulum at the [ ATP], [Mg2+], and redox conditions present in neurons ...
-
Mardones, Muriel D.; Andaur, Gabriela A.; Varas Godoy, Manuel; Henriquez, Jenny F.; Salech Morales, Felipe; Behrens Pellegrino, María Isabel; Couve Correa, Andrés; Inestrosa, Nibaldo C.; Varela Nallar, Lorena (BioMed Central Ltd., 2016)© 2016 Mardones et al. Background: In the adult hippocampus new neurons are continuously generated from neural stem cells (NSCs) present at the subgranular zone of the dentate gyrus. This process is controlled by Wnt ...
-
Ponce, Daniela P.; Salech Morales, Felipe; San Martín Rovirosa, Carol; Silva, Monica; Xiong, Chengjie; Roe, Catherine M.; Henríquez, Mauricio; Quest, Andrew F. G.; Behrens Pellegrino, María Isabel (Bentham Science Publishers B.V., 2014)© 2014 Bentham Science Publishers.We previously reported on enhanced susceptibility to death of lymphocytes from Alzheimer’s disease (AD) patients when exposed to hydrogen peroxide (H2O2)-induced oxidative stress and an ...
-
Bull Simpfendorfer, Ricardo; Finkelstein, José Pablo; Gálvez, Jorge; Sánchez, Gina; Donoso Laurent, Paulina; Behrens Pellegrino, María Isabel; Hidalgo Tapia, María Cecilia (2008)Cerebral ischemia stimulates Ca2+influx and thus increases neuronal intracellular free [Ca2+. Using a rat model of cerebral ischemia without recirculation, we tested whether ischemia enhances the activation by Ca2+ of ...
-
Pérez, María José; Ponce, Daniela P.; Aranguiz, Alejandra; Behrens Pellegrino, María Isabel; Quintanilla, Rodrigo A. (Elsevier B.V., 2018)© 2018 The Authors In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a neurodegenerative disorder, mitochondrial damage ...
-
Castillo, Sebastián; Muñoz, Patricia; Behrens Pellegrino, María Isabel; Díaz Grez, Fernando; Segura Aguilar, Juan (Springer, 2017)To explore the possible influence of heavy metal mining on incidence of Parkinson’s disease (PD), global DNA methylation was assessed in blood samples from a population of PD patients (n = 45) and control subjects (n = ...
-
Salech Morales, Felipe; Ponce, Daniela P.; San Martín Rovirosa, Carol; Rogers Castillo, Nicole; Chacón, Carlos; Henriquez Luna, Mauricio; Behrens Pellegrino, María Isabel (Frontiers media SA, 2017)Mild cognitive impairment (MCI) is a clinically detectable initial stage of cognitive deterioration with a high conversion rate to dementia. There is increasing evidence that some of the cerebral alterations present in ...
-
Behrens Pellegrino, María Isabel; Jalil, Patricio; Serani, Alejandro; Vergara, Fernando; Álvarez Araya, Osvaldo (1994)Myotonic muscular dystrophy is a genetic disease characterized mainly by muscle atrophy and myotonia, a repetitive electrical activity of muscle. In the present study, the possible role of apamin‐sensitive K+ channels in ...
-
Muñoz, Carlos; Núñez, Javier; Flores, Patricia; Behrens Pellegrino, María Isabel; Slachevsky Chonchol, Andrea (SOC MEDICA SANTIAGO, 2010-08)
-
Delgado Derio, Carolina; Araneda, A.; Behrens Pellegrino, María Isabel (Elsevier, 2019)Introducción: Existen pocas validaciones de la versión en español de la prueba Montreal Cognitive Assessment (MoCA-S) en Latinoamérica. Objetivo: Evaluar las propiedades psicométricas y la validez discriminativa del ...
-
Rogers Castillo, Nicole; San Martín Rovirosa, Carol; Ponce, D.; Henriquez Luna, Mauricio; Valdes Guerrero, Jose; Behrens Pellegrino, María Isabel (Elsevier, 2017)
-
San Martín Rovirosa, Carol; Henriquez Luna, Mauricio; Chacon, Carlos; Ponce, Daniela P.; Salech Morales, Felipe; Rogers Castillo, Nicole; Behrens Pellegrino, María Isabel (2018)Background: Mild cognitive impairment (MCI) has an increased rate of progression to dementia. Alterations of some metabolic factors, such as deficiency of vitamin D, are a risk factor for cognitive deterioration. Vitamin ...