Browsing by Author "c8bfe109-71b9-4133-957a-a123126b2e57"

Now showing items 1-6 of 6

    • Altered Steroid Metabolism and Insulin Signaling in PCOS Endometria: Impact in Tissue Function 
      Oróstica Arévalo, María Lorena; Rosas Chuñil, Carlos; Plaza Parrochia, Francisca; Astorga Leiva, Isis; Gabler Neale, Fernando; García Angulo, Víctor; Romero Osses, Carmen; Vega Blanco, María Margarita (Bentham Science, 2016)
      Background: Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine/metabolic disorder characterized by hyperandrogenemia and in most cases, by hyper-insulinemia in addition to obesity. Besides ovarian dysfunction, ...
    • Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? 
      Abello Cáceres, Paula; Pizarro Bauerle, Javier; Rosas Chuñil, Carlos Alberto; Maldonado, Ismael; Aguilar Guzmán, Lorena Andrea; González Guevara, Carlos Mauricio; Ramírez Toloza, Galia Andrea; Ferreira Parker, Jorge; Ferreira Vigouroux, Luis Arturo (2016)
      Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T. ...
    • During infection, native Trypanosoma cruzi calreticulin mediates growth inhibition of a mammary tumor 
      Abello Cáceres, Paula; Pizarro Bauerle, Javier; Rosas Chuñil, Carlos; Maldonado, I.; Roche, Sosoniuk E.; Ferreira, A. (2016)
    • Exogenous calreticulin, incorporated onto non-infective Trypanosoma cruzi epimastigotes, promotes their ... 
      Sosoniuk Roche, Eduardo Rodrigo; Vallejos, G.; Aguilar Guzmán, Lorena Andrea; Pizarro Bauerle, Javier; Weinberger, K.; Rosas Chuñil, Carlos; Valck Calderón, Carolina Eliana; Michalak, Marek (2016)
      Chagas disease is an endemic pathology in Latin America, now emerging in developed countries, causedby the intracellular protozoan Trypanosoma cruzi, whose life cycle involves three stages: amastigotes,epimastigotes, and ...
    • Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells 
      Rosas Chuñil, Carlos; Oróstica Arévalo, María Lorena; Poblete, Cristian; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Lavandero González, Sergio; Vega Blanco, María Margarita (SAGE, 2016)
      Background: Women with polycystic ovary syndrome (PCOS) exhibit a low fertility by chronic hyperandrogenemia. Different evidence have shown that androgens could regulate the endoplasmic reticulum (ER) homeostasis and glucose ...
    • Structural bases that underline trypanosoma cruzi calreticulin proinfective, antiangiogenic and antitumor ... 
      Peña Álvarez, Jaime; Teneb, Jaime; Maldonado Fuentes, Ismael; Weinberger Stange, Katherine; Rosas Chuñil, Carlos; Lemus Acuña, David; Valck Calderón, Carolina; Olivera Nappa, Álvaro; Asenjo de Leuze, Juan; Ferreira Vigouroux, Luis Arturo (Elsevier, 2020)
      Microbes have developed mechanisms to resist the host immune defenses and some elicit antitumor immune responses. About 6 million people are infected with Trypanosoma cruzi, the protozoan agent of Chagas' disease, the sixth ...