Browsing by Author "cbaa7c13-b0fd-4380-a0ed-50fc81142d90"

Now showing items 1-4 of 4

    • beta 1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel 
      Castillo, Juan P.; Sánchez Rodríguez, Jorge E.; Hyde, H. Clark; Zaelzer, Cristian A.; Aguayo, Daniel; Sepúlveda, Romina V.; Luk, Y. P.; Kent, Stephen B. H.; González Nilo, Fernando; Bezanilla, Francisco (Natl Acad Sciences, 2016)
      Large-conductance Ca2+- and voltage-activated K+ (BK) channels are involved in a large variety of physiological processes. Regulatory beta-subunits are one of the mechanisms responsible for creating BK channel diversity ...
    • Energy landscape of the reactions governing the Na + deeply occluded state of the Na +/K +-ATPase in the ... 
      Castillo, Juan P.; De Giorgis, Daniela; Basilio, Daniel; Gadsby, David C.; Rosenthal, Joshua J.C.; Latorre, Ramón; Holmgren, Miguel; Bezanill, Francisco (2011)
      The Na +/K + pump is a nearly ubiquitous membrane protein in animal cells that uses the free energy of ATP hydrolysis to alternatively export 3Na + from the cell and import 2K + per cycle. This exchange of ions produces a ...
    • Mechanism of potassium ion uptake by the Na 
      Castillo, Juan P.; Rui, Huan; Basilio, Daniel; Das, Avisek; Roux, Benoît; Latorre, Ramón; Bezanilla, Francisco; Holmgren, Miguel (Nature Publishing Group, 2015)
      © 2015 Macmillan Publishers Limited. All rights reserved. The Na<sup>+</sup>/K<sup>+</sup>-ATPase restores sodium (Na<sup>+</sup>) and potassium (K<sup>+</sup>) electrochemical ...
    • Temperature and voltage coupling to channel opening in transient receptor potential melastatin 8 (TRPM8) 
      Raddatz, Natalia; Castillo, Juan P.; González, Carlos; Álvarez Araya, Osvaldo; Latorre, Ramón (American Society for Biochemistry and Molecular Biology Inc., 2014)
      © 2014 by The American Society for Biochemistry and Molecular Biology, Inc. Expressed in somatosensory neurons of the dorsal root and trigeminal ganglion, the transient receptor potential melastatin 8 (TRPM8) channel is a ...