Now showing items 1-7 of 7

    • Acute and subchronic toxicological study of senna in rodents Toxicología aguda y subcrónica de una pasta de sen en roedores 

      Hancke, Juan; Cáceres, Dante; Burgos, Rafael A.; Hernández, Doris; Rojas, Armando; Morales, Miguel A. (2009)
      Senna crude herbal paste, CIRUELAX®, laxative used in America and Spain, was administered by oral gavage to mice and rats once daily in doses from 2 to 10 g/kg for 7 days. LD50 was rated as higher than 10 g/kg. To determine ...
    • Advanced glycation and ROS: A link between diabetes and heart failure 

      Rojas, Armando; Mercadal, Enrique; Figueroa, Hector; Morales, Miguel A. (2008)
      Despite many advances achieved to date, heart failure (HF) remains a leading cause of morbidity and mortality. There is a widely-accepted consensus that HF and diabetes are strongly linked by at least 3 mechanisms: associated ...
    • Dietary Advanced Glycation End Products and Their Role in Health and Disease 

      Uribarri, Jaime; Castillo, María Dolores del; Maza Cave, María Pía de la; Filip, Rosana; Gugliucci, Alejandro; Luevano Contreras, Claudia; Macias Cervantes, Maciste; Markowicz Bastos, Deborah; Medrano, Alejandra; Menini, Teresita; Portero Otin, Manuel; Rojas, Armando; Rodrigues Sampaio, Geni; Wrobel, Kazimierz; Wrobel, Katarzyna; Garay Sevilla, Eugenia (American Society for Nutrition, 2015)
      Over the past 2 decades there has been increasing evidence supporting an important contribution from food-derived advanced glycation end products (AGEs) to the body pool of AGEs and therefore increased oxidative stress ...
    • Facing up the ROS labyrinth - Where to go? 

      Rojas, Armando; Figueroa, Hector; Morales, Miguel A.; Re, Lamberto (2006)
      Evidence indicates that oxidative stress refers to a condition where cells are subjected to excessive levels of reactive oxygen species (ROS). Overall vascular function is dependent upon a fine balance between oxidant and ...
    • Is ozone pre-conditioning effect linked to Nrf2/EpRE activation pathway in vivo? A preliminary result 

      Re, Lamberto; Martínez-Sánchez, Gregorio; Bordicchia, Marica; Malcangi, Giuseppe; Pocognoli, Antonella; Angel Morales-Segura, Miguel; Rothchild, John; Rojas, Armando (Elsevier B.V., 2014)
      © 2014 Elsevier B.V. The present preliminary study has been focused on verifying whether ozone preconditioning may be linked to Nrf2/EpRE (nuclear factor erythroid 2/electrophile-responsive element) activation pathway in ...
    • Oxidative stress at the vascular wall. Mechanistic and pharmacological aspects 

      Rojas, Armando; Figueroa, Héctor; Re, Lamberto; Morales, Miguel A. (ELSEVIER, 2006-05)
      During the process of energy production in aerobic respiration, vascular cells produce reactive oxygen species (ROS). A growing body of evidence indicates that oxidative stress refers to a condition in which cells are ...
    • Oxidative stress in tumor microenvironment -- Its role in angiogenesis 

      Rojas, Armando; Silva, Raúl; Figueroa, Héctor; Morales, Miguel A. (2008)
      The tumor angiogenesis process is believed to be dependent on an "angiogenic switch" formed by a cascade of biologic events as a consequence of the "cross-talk" between tumor cells and several components of local ...