Browsing by Author "cd44a5a3-2105-4576-adf9-de00b4ee78dd"

Now showing items 1-3 of 3

    • Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells ... 
      Jara, Claudia; Oyarzún Ampuero, Felipe; Carrión, Flavio; González Echeverría, Esteban; Cappelli, Claudio; Caviedes Fernández, Pablo (BMC, 2020)
      Background: In type I diabetes mellitus (T1DM) pancreatic beta cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet ...
    • Palmitic acid reduces the autophagic flux in hypothalamic neurons by impairing autophagosome-lysosome fusion ... 
      Hernández Cáceres, María Paz; Cereceda, Karina; Hernández, Sergio; Li, Ying; Narro, Carla; Rivera, Patricia; Silva, Patricio; Ávalos, Yenniffer; Jara, Claudia; Burgos, Paulina; Toledo Valenzuela, Lilian; Lagos, Pablo; Cifuentes Araneda, Flavia; Pérez Leighton, Claudio; Bertocchi, Cristina; Clegg, Deborah J.; Criollo Céspedes, Alfredo; Tapia Rojas, Cheril; Burgos, Patricia V.; Morselli, Eugenia (Taylor & Francis, 2020)
      High-fat diet (HFD)-induced obesity is associated with increased cancer risk. Long-term feeding with HFD increases the concentration of the saturated fatty acid palmitic acid (PA) in the hypothalamus. We previously showed ...
    • PGC-1α-dependent mitochondrial adaptation is necessary to sustain IL-2-induced activities in human NK cells 
      Miranda, Dante; Jara, Claudia; Ibañez, Jorge; Ahumada, Viviana; Acuña Castillo, Claudio; Martin, Adrian; Córdova, Alexandra; Montoya, Margarita (Hindawi Publishing Corporation, 2016)
      Human Natural Killer (NK) cells are a specialized heterogeneous subpopulation of lymphocytes involved in antitumor defense reactions. NK cell effector functions are critically dependent on cytokines and metabolic activity. ...