Browsing by Author "def5a749-4275-4fae-b8d0-cd1365892f85"

Now showing items 1-9 of 9

    • A regulatory RNA is involved in RNA duplex formation and biofilm regulation in sulfolobus acidocaldarius 
      Orell, Alvaro; Tripp, Vanessa; Aliaga-Tobar, Victor; Albers, Sonja-Verena; Maracaja Coutinho, Vinicius; Randau, Lennart (Oxford University Press, 2018-05-18)
      Non-coding RNAs (ncRNA) are involved in essential biological processes in all three domains of life. The regulatory potential of ncRNAs in Archaea is, however, not fully explored. In this study, RNA-seq analyses identified ...
    • An additive effect of ebv-miR-BART5-5p and hsa-miR18a-5p in the downregulation of CDH1 transcript in ... 
      Torres, Keila; Landeros, Natalia; Wichmann, Ignacio; Peñaloza Otárola, Allan; Polakovicova, Iva; Maracaja Coutinho, Vinicius; Maturana, María José; Villaroel Espíndola, Franz; Corvalán, Alejandro (AMER Assoc Cancer Research, 2020)
    • Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA ... 
      Sotomayor Flores, Cristian; Rivera Mejías, Pablo; Vásquez Trincado, César; López Crisosto, Camila; Morales, Pablo E.; Pennanen, Christian; Polakovicova, Iva; Aliaga Tobar, Víctor; García Nannig, Lorena; Roa, Juan Carlos; Rothermel, Beverly A.; Maracaja Coutinho, Vinicius; Ho-Xuan, Hung; Meister, Gunter; Chiong, Mario; Ocaranza, María Paz; Corvalán, Alejandro H.; Parra Ortiz, Valentina; Lavandero González, Sergio (2020)
      Angiotensin-(1-9) is a peptide from the noncanonical renin-angiotensin system with anti-hypertrophic effects in cardiomyocytes via an unknown mechanism. In the present study we aimed to elucidate it, basing us initially ...
    • Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein 
      Gómez, Wileidy; Morales, Rodrigo; Maracaja Coutinho, Vinicius; Parra Ortiz, Valentina; Nassif, Melissa (Impact Journals LLC, 2020)
      Alzheimer’s disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. ...
    • Editorial: User-friendly tools applied to genetics or systems biology 
      Nakaya, Helder I.; Thakar, Juilee; Maracaja Coutinho, Vinicius (Frontiers Media, 2020)
    • Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral ... 
      Matamala, José Manuel; Arias Carrasco, Raul; Sánchez, Carolina; Uhrig, Markus; Bargsted, Leslie; Matus, Soledad; Maracaja Coutinho, Vinicius; Abarzua, Sebastián; Van Zundert, Brigitte; Verdugo Latorre, Renato; Manque, Patricio; Hetz Flores, Claudio (Elsevier, 2018)
      The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...
    • Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci 
      Amaral, Paulo P.; Leonardi, Tommaso; Han, Namshik; Vire, Emmanuelle; Gascoigne, Dennis K.; Arias Carrasco, Raúl; Buscher, Magdalena; Pandolfini, Luca; Zhang, Anda; Pluchino, Stefano; Maracaja Coutinho, Vinicius; Nakaya, Helder I.; Hemberg, Martin; Shiekhattar, Ramin; Enright, Anton J.; Kouzarides, Tony (BIOMED Central Ltd., 2018)
      Background: The mammalian genome is transcribed into large numbers of long noncoding RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly due to their low sequence conservation and ...
    • Human adipose-derived mesenchymal stem cell-conditioned medium ameliorates polyneuropathy and foot ulceration ... 
      De Gregorio, Cristián; Contador, David; Díaz, Diego; Cárcamo, Constanza; Santapau, Daniela; Lobos González, Lorena; Acosta, Cristián; Campero Soffia, Mario; Carpio, Daniel; Gabriele, Caterina; Gaspari, Marco; Aliaga Tobar, Víctor; Maracaja Coutinho, Vinicius; Ezquer, Marcelo; Ezquer, Fernando (BMC, 2020)
      Background Diabetic polyneuropathy (DPN) is the most common and early developing complication of diabetes mellitus, and the key contributor for foot ulcers development, with no specific therapies available. Different studies ...
    • StructRNAfinder: an automated pipeline and web server for RNA families prediction 
      Arias Carrasco, Raúl; Vásquez Moran, Yessenia; Nakaya, Helder I.; Maracaja Coutinho, Vinicius (BIOMED Central Ltd., 2018)
      Background: The function of many noncoding RNAs (ncRNAs) depend upon their secondary structures. Over the last decades, several methodologies have been developed to predict such structures or to use them to functionally ...