Now showing items 1-2 of 2

    • Calcium sensing receptor activation in THP-1 macrophages triggers NLRP3 inflammasome and human preadipose cell inflammation 

      D'Espessailles Tapia, Amanda; Santillana, Natalia; Sanhueza, Sofía; Fuentes, Cecilia; Cifuentes Koster, Mariana (Elsevier, 2020)
      Excess adipose tissue (AT) associates with inflammation and obesity-related diseases. We studied whether calcium-sensing receptor (CaSR)-mediated NLRP3 inflammasome activation in THP-1 macrophages elevates inflammation in ...
    • Is mitochondrial dysfunction a common root of noncommunicable chronic diseases? 

      Díaz Vegas, Alexis; Sánchez Aguilera, Pablo; Krycer, James R; Morales, Pablo E.; Monsalves Álvarez, Matías; Cifuentes Koster, Mariana; Rothermel, Beverly A.; Lavandero González, Sergio (Endocrine Society, 2020)
      Mitochondrial damage is implicated as a major contributing factor for a number of noncommunicable chronic diseases such as cardiovascular diseases, cancer, obesity, and insulin resistance/type 2 diabetes. Here, we discuss ...