Now showing items 1-10 of 10

    • Changes in ethical attitudes during medical studies Cambios de actitudes éticas a lo largo de los estudios de medicina. 

      Kottow,; Alvarez Alvarez, Miguel Adrián; Santander Santander, Connie; Urrutia,; Cumsille,; Roa, (1993)
      The aim of this work was to explore the attitude changes towards ethico-medical issues in medical students as they went through medical school. A personal standardized questionnaire containing 14 closed and direct questions ...
    • Early gallbladder cancer: Is further treatment necessary? 

      Aretxabala, Xabier de; Roa, Ivan; Hepp, Juan; Maluenda, Fernando; Mordojovich, Gerardo; Leon, Jorge; Roa, Juan (2009)
      Background and Objectives: The goal of this study was to evaluate a series of patients with early gallbladder cancer, focusing on the selection of treatment and the role of Rokitansky Aschoff sinus infiltration. Methods: ...
    • Gallbladder cancer: An analysis of a series of 139 patients with invasion restricted to the subserosal layer 

      Aretxabala, Xabier de; Roa, Iván; Burgos, Luis; Losada, Héctor; Roa, Juan Carlos; Mora, Javier; Hepp, Juan; León, Jorge; Maluenda, F. (ELSEVIER, 2006-02)
      The goal was to study our experience in the management of a series of patients with a potentially curative subscrosal gallbladder cancer who were prospectively treated by the authors. Between April 1988 and July 2004, 139 ...
    • HPV genotyping from invasive cervical cancer in Chile 

      Roa, Juan; Garcia, Patricia; Gomez, Jorge; Fernández, Wanda; Gaete, Fancy; Espinoza, Arturo; Lepetic, Alejandro; Suarez, Eugenio (John Wiley and Sons Ltd, 2009)
      Objective: To determine the prevalence rates of the different HPV types in cervical cancer lesions in Chile to facilitate the development of prophylactic human papillomavirus (HPV) vaccines effective for that country. ...
    • Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor Progression and p73 Expression in Gastric Cancer 

      Saavedra, Kathleen; Valbuena, José; Olivares, Wilda; Marchant, María José; Rodríguez, Andrés; Torres Estay, Verónica; Carrasco Avino, Gonzalo; Guzmán, Leda; Aguayo González, Francisco; Roa, Juan Carlos; Corvalán, Alejandro H. (Public Library Science, 2015)
      Reprimo (RPRM), a downstream effector of p53-induced cell cycle arrest at G2/M, has been proposed as a putative tumor suppressor gene (TSG) and as a potential biomarker for non-invasive detection of gastric cancer (GC). ...
    • MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer 

      Sandoval Borquez, Alejandra; Polakovicova, Iva; Carrasco Véliz, Nicolás; Lobos González, Lorena; Riquelme, Ismael; Carrasco Aviño, Gonzalo; Bizama, Carolina; Norero, Enrique; Owen, Gareth I.; Roa, Juan; Corvalán, Alejandro H. (Biomed Central Ltd., 2017)
      Background: Multiple aberrant microRNA expression has been reported in gastric cancer. Among them, microRNA-335-5p (miR-335), a microRNA regulated by DNA methylation, has been reported to possess both tumor suppressor and ...
    • Recomendaciones sobre el manejo del cáncer de páncreas tipo adenocarcinoma en Latinoamérica. Reunión del Consenso del Simposio Latinoamericano de Gastroenterología Oncológica (SLAGO) y de la Asociación Ibero Latinoamericana de Terapia Radiante (ALATRO), Viña del Mar, Chile 2015 

      Caglevic, Christian; Gallardo, Jorge; de la Torre, Marcela; Mahave, Mauricio; Müller, Bettina; Solé, Sebastián; Moscoso, Yuri; De La Fuente, Hernán; Roa, Juan Carlos; Hoefler, Sebastián; Butte, Jean; González, Pablo; O´Connor, Juan Manuel; Torres, Javiera; Pérez Encalada, Verónica; Alarcón Cano, Daniel; Ubillos, Luis; Rolfo, Christian; Lingua, Alejo; Díaz Romero, Consuelo; Padilla Rosciano, Alejandro; Cuartero, Viviana; Calderillo Ruiz, Germán; Schwartsmann, Gilberto; Kon Jara, Xavier; Andrade G., Andrés; Mas López, Luis; Barajas Barajas, Olga; Carballido, Marcela; Lembach Jahnsen, Hanns; Morillas G., Lena; Roca, Enrique; Lobatón, José; Montenegro B., Paola; Yepes, Andrés; Marsiglia, Hugo (Sociedad Médica de Santiago, 2016)
      Pancreatic cancer is a malignancy of great impact in developed countries and is having an increasing impact in Latin America. Incidence and mortality rates are similar for this cancer. This is an important reason to offer ...
    • Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024 

      Ferreccio, Catterina; Roa, Juan Carlos; Bambs, Claudia; Vives, Alejandra; Corvalán, Alejandro H.; Cortés, Sandra; Foerster, Claudia; Acevedo, Johanna; Huidobro, Andrea; Passi, Alvaro; Toro, Pablo; Covacevich, Yerko; Cruz, Rolando de la; Koshiol, Jill; Olivares, Mauricio; Miquel, Juan Francisco; Cruz, Francisco; Silva, Raúl; Quest, Andrew F. G.; Kogan Bocian, Marcelo; Castro, Pablo F.; Lavandero González, Sergio (BioMed Central, 2016)
      Background: Maule Cohort (MAUCO), a Chilean cohort study, seeks to analyze the natural history of chronic diseases in the agricultural county of Molina (40,000 inhabitants) in the Maule Region, Chile. Molina's population ...
    • The relationship between chemokines CCL2, CCL3, and CCL4 with the tumor microenvironment and tumor-associated macrophage markers in colorectal cancer 

      De la Fuente López, Marjorie; Landskron, Glauben; Parada, Daniela; Dubois Camacho, Karen; Simian, Daniela; Martinez, Maripaz; Romero, Diego; Roa, Juan; Chahuán, Isidora; Gutiérrez, Rocío; Lopez-K, Francisco; Alvarez, Karin; Kronberg, Udo; López, Sebastián; Sangu (NLM (Medline), 2018)
      A complex network of chemokines can influence cancer progression with the recruitment and activation of hematopoietic cells, including macrophages to the supporting tumor stroma promoting carcinogenesis and metastasis. The ...
    • Tumor lysate-based vaccines: on the road to immunotherapy for gallbladder cancer 

      Rojas-Sepúlveda, Daniel; Tittarelli, Andrés; Gleisner, María Alejandra; Ávalos, Ignacio; Pereda, Cristián; Gallegos, Iván; González, Fermín Eduardo; López, Mercedes Natalia; Butte, Jean Michel; Roa, Juan; Fluxá, Paula; Salazar Onfray, Flavio (Springer Science and Business Media Deutschland GmbH, 2018)
      © 2018, The Author(s). Immunotherapy based on checkpoint blockers has proven survival benefits in patients with melanoma and other malignancies. Nevertheless, a significant proportion of treated patients remains refractory, ...