Browsing by Author "e16a4be5-820c-44cf-aa5f-27f8267db40f"

Now showing items 1-6 of 6

    • Biomimetic quantum dot-labeled B16F10 murine melanoma cells as a tool to monitor early steps of lung ... 
      Díaz García, Víctor; Guerrero, Simón; Díaz Valdivia, Natalia; Lobos González, Lorena; Kogan Bocian, Marcelo; Pérez Donoso, José; Quest, Andrew F. G. (NLM (Medline), 2018)
      Background: Numerous studies have proposed the use of fluorescent semiconductor nanoparticles or quantum dots (QDs) as novel tools to label cells and tumors. However, QD applications are limited by their toxicity in ...
    • Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor 
      Prades, Roger; Guerrero, Simón; Araya, Eyleen; Molina, Claudia; Salas, Edison; Zurita, Esther; Selva, Javier; Egea, Gustavo; López-Iglesias, Carmen; Teixidó, Meritxell; Kogan Bocian, Marcelo; Giralt, Ernest (2012)
      The treatment of Alzheimer's disease and many other brain-related disorders is limited because of the presence of the blood-brain barrier, which highly regulate the crossing of drugs. Metal nanoparticles have unique features ...
    • Flow chemistry to control the synthesis of nano and microparticles for biomedical applications 
      Hassan, Natalia; Oyarzún Ampuero, Felipe; Muñoz Lara, Pablo; Guerrero, Simón; Cabuil, Valérie; Abou-Hassan, Ali; Kogan Bocian, Marcelo (Bentham Science Publishers B.V., 2014)
      In this article we review the flow chemistry methodologies for the controlled synthesis of different kind of nano and microparticles for biomedical applications. Injection mechanism has emerged as new alternative for the ...
    • Gold nanoparticle based double‑labeling of melanoma extracellular vesicles to determine the specificity of ... 
      Lara, Pablo; Palma Florez, Sujey; Salas Huenuleo, Edison; Polakovicova, Iva; Guerrero, Simón; Lobos González, Lorena; Campos, América; Muñoz, Luis; Jorquera Cordero, Carla; Varas Godoy, Manuel; Cancino, Jorge; Arias, Eloísa; Villegas, Jaime; Cruz, Luis J.; Albericio, Fernando; Araya, Eyleen; Corvalán, Alejandro H.; Quest, Andrew F. G.; Kogan Bocian, Marcelo (BMC, 2020)
      Background Extracellular vesicles (EVs) have shown great potential for targeted therapy, as they have a natural ability to pass through biological barriers and, depending on their origin, can preferentially accumulate at ...
    • Gold nanoparticles as tracking devices to shed light on the role of caveolin-1 in early stages of melanoma ... 
      Guerrero, Simón; Díaz García, Víctor; Contreras-Orellana, Pamela; Muñoz Lara, Pablo; Palma, Sujey; Guzmán, Fanny; Lobos González, Lorena; Cárdenas, Areli; Rojas Silva, Ximena; Muñoz, Luis; Leyton Campos, Lisette; Kogan Bocian, Marcelo; Quest, Andrew F. G. (Future Medicine, 2018-06)
      Aim: To track early events during lung metastasis, we labeled cells expressing (B16F10(CAV1)) or lacking CAV1 (B16F10(mock)) with gold nanoparticles conjugated to the peptide TAT (AuNPs-PEG-TAT). Methods: B16F10 expressing ...
    • Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells 
      Ortiz, Rina; Díaz, Jorge; Díaz Valdivia, Natalia; Martínez Meza, Samuel; Simón, Layla; Contreras Orellana, Pamela; Lobos González, Lorena; Guerrero, Simón; Leyton Campos, Lisette; Quest, Andrew F. G. (Elsevier, 2020)
      In advanced stages of cancer disease, caveolin-1 (CAV1) expression increases and correlates with increased migratory and invasive capacity of the respective tumor cells. Previous findings from our laboratory revealed that ...