Now showing items 1-4 of 4

    • Cortés, Nicole; Andrade, Víctor; Maccioni Baraona, Ricardo (IOS Press, 2018)
      Alzheimer's disease (AD) is the most frequent type of dementia in the elderly, severely affecting functional and executive skills of subjects suffering from this disease. Moreover, the distress of caregivers as well as the ...
    • Cortés, Nicole; Guzmán Martínez, Leonardo; Andrade, Víctor; González, Andrea; Maccioni Baraona, Ricardo (IOS Press, 2019)
      The cyclin-dependent kinase 5 (CDK5) is known as an exceptional component of the CDK family, due to its characteristic regulatory pathways and its atypical roles in comparison to the classical cyclins. Despite its functional ...
    • Andrade, Víctor; Cortés, Nicole; Pastor, Gabriela; González, Andrea; Ramos Escobar, Nicolás; Pastene, Edgar; Rojo, Leonel E.; Maccioni Baraona, Ricardo (IOS Press, 2020)
      Background: Alzheimer's disease (AD) is a multifactorial disease, that involves neuroinflammatory processes in which microglial cells respond to "damage signals". The latter includes oligomeric tau, iron, oxidative free ...
    • Morales, Inelia; Cerda Troncoso, Cristóbal; Andrade, Víctor; Maccioni Baraona, Ricardo (IOS Press, 2017)
      Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive cognitive impairment of patients, affecting around 12% of people older than 65 years old. WHO estimated that over 48.6 million all over ...