Browsing by Author "e8bee92d-aa64-4ecf-bbf7-4c8d06346fdd"
Now showing items 1-13 of 13
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Reyna Gallegos, Sixto; Torres Arrunátegui, Génesis; Valenzuela, Rodrigo; Rincón Cervera, Miguel Ángel; Villanueva Espinoza, María Elena (Elsevier, 2018-05)Flavonoids upregulate gene expression of PPAR-alpha and underregulate the gene expression of SREBP-lc, and their intake increases the plasmatic concentration of n-3 LC-PUFAs. However, the biological mechanisms underlying ...
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Rincón Cervera, Miguel Ángel; Galleguillos-Fernández, Raúl; González-Barriga, Valeria; Valenzuela, Rodrigo; Valenzuela Bonomo, Carlos (Wiley-VCH Verlag, 2018)© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim In this work, gamma-linolenic acid (GLA) and stearidonic acid (SDA) are successfully concentrated as free fatty acids (FFA) and ethyl esters (EE) using the urea complexation ...
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Espinosa, Alejandra; Ross, Andrés; Dovale-Rosabal, Gretel; Pino De la Fuente, Francisco Javier; Uribe Oporto, Ernesto; Sacristán, Camila; Ruiz Rojas, Paulina; Valenzuela, Rodrigo; Romero Palacios, Nalda; Aubourg, Santiago P.; Rodríguez Melis, Alicia (MDPI, 2020)Dietary intake of eicosapentaenoic/docosahexaenoic acid (EPA/DHA) reduces insulin resistance and hepatic manifestations through the regulation of metabolism in the liver. Obese mice present insulin resistance and lipid ...
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Jaramillo, Ángela M.; Garmendia Miguel, MarÍa Luisa; Muñoz, Patricio; Corbari, Alicia; Valenzuela, Rodrigo; Casanello, Paola (Wiley, 2020)The interest in the amount of polyunsaturated fatty acids (PUFA) in the umbilical cord blood (UCB) is increasing, but the stability of erythrocyte PUFA in these samples during storage and washing of the erythrocytes has ...
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Troncoso Cotal, Rodrigo; Moraga, Francisco; Chiong Lay, Mario; Roldán, Juan; Bravo, Roberto; Valenzuela, Rodrigo; Díaz Araya, Guillermo; Del Campo, Andrea; Sanhueza, Carlos; Rodriguez, Andrea; Vukasovic, José Luis; Mellado, Rosemarie; Greig, Douglas; Castro, Pablo F.; Lavandero González, Sergio (2009)We investigated the clinical response of chronic heart failure patients with β2-adrenergic receptor Gln27→Glu polymorphism treated for 6 months with carvedilol, a α/β-antagonist with antioxidant properties. The 6-min. walk ...
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Álvarez, Daniela; Muñoz, Yasna; Ortiz, Macarena; Maliqueo Yevilao, Manuel; Chouinard Watkins, Raphael; Valenzuela, Rodrigo (MDPI, 2021)Prenatal and postnatal development are closely related to healthy maternal conditions that allow for the provision of all nutritional requirements to the offspring. In this regard, an appropriate supply of fatty acids (FA), ...
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Lipid droplets are both highly oxidized and Plin2-covered in hepatocytes of diet-induced obese mice Nocetti, Diego; Espinosa, Alejandra; Pino de la Fuente, Francisco; Sacristán, Camila; Bucarey, José Luis; Ruiz, Paulina; Valenzuela, Rodrigo; Chouinard Watkins, Raphael; Pepper Bergholz, Inés; Troncoso, Rodrigo; Puente Díaz, Luis (Canadian Science Publishing, 2020)Chronic high-fat diet feeding is associated with obesity and accumulation of fat in the liver, leading to the development of insulin resistance and nonalcoholic fatty liver disease. This condition is characterized by the ...
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Valenzuela, Rodrigo; Das, Undurti N.; Videla Cabrera, Luis; Llorente, Carolina G. (Hindawi, 2018)
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Prevention of liver ischemia reperfusion injury by a combined thyroid hormone and fish oil protocol Mardones, Marcelo; Valenzuela, Rodrigo; Romanque, Pamela; Covarrubias, Natalia; Anghileri, Fiorella; Fernández Arancibia, Virginia; Videla Cabrera, Luis; Tapia Opazo, Gladys (2012)Several preconditioning strategies are used to prevent ischemia-reperfusion (IR) liver injury, a deleterious condition associated with tissue resection, transplantation or trauma. Although thyroid hormone (T3) administration ...
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Zúñiga, Jessica; Venegas, Francisca; Villarreal, Marcela; Núñez, Daniel; Chandía, Marlene; Valenzuela, Rodrigo; Tapia Opazo, Gladys; Varela, Patricia; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2010)N-3 polyunsaturated fatty acids (n-3 PUFA) affect inflammatory processes. This study evaluated the effects of dietary supplementation with fish oil on hepatic ischemia-reperfusion (IR) injury in the rat. Parameters of liver ...
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Valenzuela, Rodrigo; Ortiz, Macarena; Hernández-Rodas, María Catalina; Echeverría, Francisca; Videla, Luis A. (Bentham Science, 2020)Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is characterized by abnormal hepatic accumulation of triacylglycerides in the absence of alcohol consumption, in association with Oxidative Stress (OS), a pro-inflammatory ...
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Valenzuela, Rodrigo; Videla Cabrera, Luis (Royal Society of Chemistry, 2011)Non-alcoholic fatty liver disease (NAFLD) is the most important cause of chronic liver disease that is characterized by hepatocyte triacylglycerol accumulation (steatosis), which can progress to inflammation, fibrosis, and ...
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Illesca, Paola; Valenzuela, Rodrigo; Espinosa, Alejandra; Echeverría, Francisca; Soto Alarcón, Sandra A.; Ortiz, Macarena; Campos, Cristian; Vargas, Romina; Videla Cabrera, Luis (Royal Society of Chemistry, 2020)Background: Nutritional interventions are promising tools for the prevention of obesity. The n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) docosahexaenoic acid (DHA) modulates immune and metabolic responses while ...