Now showing items 1-5 of 5

    • Emingil, Gülnur; Gürkan, Ali; Tervahartiala, Taina; Hernández, Marcela; Özgül, Semiha; Sorsa, Timo; Alassiri, Saeed (MDPI Multidisciplinary Digital Publishing Institute, 2019)
      Objectives: The aim of the present randomized, double-blind, placebo-controlled, parallel-arm study was to examine the effectiveness of a sub-antimicrobial dose of doxycycline (SDD) in combination with nonsurgical periodontal ...
    • Leppilahti, Jussi; Hernández Ríos, Patricia; Gamonal Aravena, Jorge Antonio; Tervahartiala, Taina; Brignardello Petersen, Romina; Mantyla, Paivi; Sorsa, Timo; Hernández, Marcela (2014)
      Aim: To identify the diagnostic accuracy of gingival crevicular fluid (GCF) candidate biomarkers to discriminate periodontitis from the inflamed and healthy sites, and to compare the performance of two independent matrix ...
    • Hernández, Marcela; Baeza Paredes, Mauricio; Contreras Balbontín, Johanna; Sorsa, Timo; Tervahartiala, Taina; Valdés Salgado, Macarena; Chaparro, Alejandra; Hernández Ríos, Patricia (MDPI, 2020)
      Biomarkers represent promising aids in periodontitis, host-mediate diseases of the tooth-supporting tissues. We assessed the diagnostic potential of matrix metalloproteinase-8 (MMP-8), tartrate-resistant acid phosphatase-5 ...
    • Listyarifah, Dyah; Nieminen, Mikko; Mäkinen, Laura; Haglund, Caj; Grenier, Daniel; Häyry, Valtteri; Nordström, Dan; Hernandez, Marcela; Yucel-Lindberg, Tülay; Tervahartiala, Taina; Ainola, Mari; Sorsa, Timo; Hagström, Jaana (Blackwell Publishing Ltd, 2018)
      Background: Certain periodontopathogenic bacteria have been linked to cancers. Treponema denticola (Td) is associated with severe periodontitis. Chymotrypsin-like proteinase (CTLP), a major virulence factor of Td, can ...
    • Nieminen, Mikko T.; Listyarifah, Dyah; Hagstrom, Jaana; Haglund, Caj; Grenier, Daniel; Nordstrom, Dan; Uitto, Veli-Jukka; Hernández Ríos, Emma; Yucel-Lindberg, Tulay; Tervahartiala, Taina; Ainola, Mari; Sorsa, Timo (Nature, 2018)
      Background: Periodontal pathogens have been linked to oral and gastrointestinal (orodigestive) carcinogenesis. However, the exact mechanisms remain unknown. Treponema denticola (Td) is associated with severe periodontitis, ...